Postnatal litter size effects on growth and reproduction in rats

Journal of Animal Science
S M AzzamG E Dickerson

Abstract

The effects of postnatal litter size on pre- and postweaning growth, daughter's litter size and rebreeding performance of the dam were examined in rats that had undergone 14 generations of selection for rate (LG) or efficiency (LE) of postweaning protein gain followed by relaxed selection, and in a randomly selected control line (C). Data came from generations 23 to 24 (standardized litters) and 25 to 26 (unstandardized litters). Generation 25 dams were remated at weaning for two additional parities. Regressions of average pup weight on average postnatal litter size were negative and increased in magnitude from birth to weaning, but decreased with parity number. Average litter size from birth to weaning (3 wk) affected postweaning weights at 5 and 7 wk, but compensatory growth occurred, especially during wk 3 to 5. The effect of dam's litter size (the litter in which the daughter was born) on daughter's weight was still negative and significant at mating and affected litter size of daughters. This negative maternal effect on daughter's litter size was larger when the dam's litter was not standardized. Litter size weaned also affected rebreeding interval of females.

Citations

Aug 26, 2011·Developmental Psychobiology·Heiko G Rödel, Susann Meyer
Oct 16, 2002·Drug and Chemical Toxicology·Elise M LewisMildred S Christian
May 14, 2016·Endocrinology·Alexander Suvorov, Laura N Vandenberg
Mar 20, 2013·BioMed Research International·Albert H-L ChanJan C C Hu
Nov 27, 2020·Frontiers in Psychiatry·Francisco NavarreteJorge Manzanares

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.