Postnatal nutritional treatment of neurocognitive deficits in fetal alcohol spectrum disorder

Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
A Bastons-ComptaO Garcia-Algar

Abstract

Ethanol is the most important teratogen agent in humans. Prenatal alcohol exposure can lead to a wide range of adverse effects, which are broadly termed as fetal alcohol spectrum disorder (FASD). The most severe consequence of maternal alcohol abuse is the development of fetal alcohol syndrome, defined by growth retardation, facial malformations, and central nervous system impairment expressed as microcephaly and neurodevelopment abnormalities. These alterations generate a broad range of cognitive abnormalities such as learning disabilities and hyperactivity and behavioural problems. Socioeconomic status, ethnicity, differences in genetic susceptibility related to ethanol metabolism, alcohol consumption patterns, obstetric problems, and environmental influences like maternal nutrition, stress, and other co-administered drugs are all factors that may influence FASD manifestations. Recently, much attention has been paid to the role of nutrition as a protective factor against alcohol teratogenicity. There are a great number of papers related to nutritional treatment of nutritional deficits due to several factors associated with maternal consumption of alcohol and with eating and social disorders in FASD children. Although research...Continue Reading

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Citations

Aug 4, 2018·Nutrients·Giorgia SebastianiOscar García-Algar
Apr 30, 2019·Birth Defects Research·Shama BhatiaPeter G Wells
Dec 4, 2019·Current Opinion in Endocrinology, Diabetes, and Obesity·Joshua J Baker, Joan M Stoler
Feb 7, 2021·International Journal of Environmental Research and Public Health·Joan ColomOscar Garcia-Algar
Mar 23, 2021·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Silvia Maya-EneroÓscar García-Algar
Aug 31, 2021·Anales De Pediatría·Silvia Maya-EneroÓscar García-Algar

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