PMID: 39983Sep 1, 1979

Postnatal rat sympathetic neurons in culture. I. A comparison with embryonic neurons

Journal of Neurophysiology
E WakshullH Burton

Abstract

1. A morphological and physiological comparison was made between embryonically and postnatally derived superior cervical ganglion neurons (SCGN) grown in dissociated cell culture. It was found that while morphologically distinct, the physiological properties of the postnatal neurons were the same as their embryonic counterparts. 2. Intracellular injection of horseradish peroxidase (HPR) demonstrated that SCGN from any age of animal elaborated two basic types of processes, although the pattern of process ramification was unique for each neuron. The two types of proceses were 1) the large, smooth, rapidly tapering; and 2) the thin, nontapering variety, which often contained varicosities along its length. It is suggested that the former are dendritic in function, while the latter act as axons. 3. A difference was noted in somal size and the number of primary processes extended by the embryonic and postnatal neurons, with the latter more closely resembling the in vivo morphology. 4. Resting potentials and action-potential amplitudes of postnatal SCGN were comparable to those found previously for embryonic SCGN in vitro. 5. Iontophoretic application of putative neurotransmitter substances revealed the presence of acetylcholine recep...Continue Reading

References

Jan 1, 1986·Annals of the New York Academy of Sciences·S T Brady, M M Black
Apr 9, 1999·Nature Neuroscience·J M IlardiZ H Sheng
May 1, 1988·Pflügers Archiv : European journal of physiology·G G Schofield, S R Ikeda
May 1, 1991·Visual Neuroscience·A T Ishida, M H Cheng

Related Concepts

Embryo
Fluctuation
Depression, Postpartum
Science of Morphology
Protoplasm
Resting Potentials
Neurons
Cell Culture Techniques
Synaptic Transmission
Picrotoxin

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