Postneuroleptic laryngeal dyskinesias: a cause of upper airway obstructive syndrome improved by local injections of botulinum toxin

Movement Disorders : Official Journal of the Movement Disorder Society
A FèveJ Lacau Saint-Guily

Abstract

We report a case of laryngeal dyskinesia resulting in severe rest and exercise dyspnea. A 51-year-old man treated for 2 years with flupentixol, an incisive neuroleptic, developed severe dyspnea due to intermittent, rhythmic, and dystonic movements of the vocal cords and upper airway. Local injections of botulinum toxin resulted in spectacular regression of laryngeal spasms and major improvement in breathing. This case emphasizes the risk of upper respiratory dyskinesias associated with neuroleptic treatment and shows the feasibility of a new local treatment in this life-threatening disorder.

References

Mar 1, 1978·Annals of Internal Medicine·W J WeinerH L Klawans
Apr 1, 1978·The American Journal of Psychiatry·D E Casey, P Rabins
Nov 1, 1978·The American Journal of Psychiatry·J A Flaherty, H W Lahmeyer
Nov 28, 1990·JAMA : the Journal of the American Medical Association·C L Ludlow
Jan 1, 1987·Movement Disorders : Official Journal of the Movement Disorder Society·M R SamieS Rozek
Jun 1, 1987·Archives of Otolaryngology--head & Neck Surgery·R H MillerJ Jankovic
Apr 1, 1982·The American Journal of Psychiatry·A D FaheemA Struss
Aug 16, 1984·The New England Journal of Medicine·W G VinckenM G Cosio

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Citations

Sep 24, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·P KañovskýH Hortová
May 1, 1994·Movement Disorders : Official Journal of the Movement Disorder Society·M F LewC H Waters
Nov 1, 1995·Movement Disorders : Official Journal of the Movement Disorder Society·A LaguenyJ Julien
Jul 1, 1995·Journal of Neurology·A FèveJ Lacau St Guily
Nov 19, 2008·Journal of Neurology·Kathleen L Poston, Steven J Frucht
Jul 1, 2005·Current Neurology and Neuroscience Reports·Steven J Frucht
Nov 22, 1997·The Laryngoscope·D A MaschkaR J Smith
Jan 1, 1997·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·P ZwirnerE Kruse
Oct 16, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Johannes M H HenningsThomas C Wetter
Jun 4, 2008·Expert Opinion on Pharmacotherapy·Praveen Dayalu, Kelvin L Chou
Jul 8, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·Ambar Chakravarty
Sep 8, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Virginie WoisardMarion Simonetta-Moreau
Jul 21, 2021·Expert Review of Neurotherapeutics·Muhammad Ubaid HafeezJoseph Jankovic

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