Postoperative analgesic effect of preoperative intravenous flurbiprofen in arthroscopic rotator cuff repair.

Journal of Anesthesia
Masafumi TakadaKoji Sumikawa

Abstract

This study was carried out to evaluate the postoperative analgesic effects of preoperative intravenous flurbiprofen in patients undergoing arthroscopic rotator cuff repair under general anesthesia. We studied 44 patients who underwent an elective arthroscopic rotator cuff repair in a prospective, randomized, and double-blind fashion. The patients were divided into two groups. Group A (n = 22) received lipid emulsion 0.1 ml kg(-1) as a placebo, and group B (n = 22) received flurbiprofen 1 mg kg(-1) before the surgery. Intralipid or flurbiprofen was given intravenously 5 min before the surgery. General anesthesia was maintained with sevoflurane and nitrous oxide, and 10 ml of 0.75% ropivacaine was administered intraarticularly at the end of the surgery. Postoperative analgesia was supplied with intravenous 0.1 mg buprenorphine according to the patient's demand. The effectiveness of flurbiprofen's analgesic effect was measured by a visual analog scale (VAS) and by the amount of buprenorphine consumption at 0.5, 1, 2, 4, 6, 12, and 24 h after the surgery. Time to the first analgesic was also recorded. VAS in group B was significantly (P < 0.01) lower than that in group A during the first 6 h postoperatively. The amount of buprenorp...Continue Reading

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Citations

Apr 16, 2016·Journal of Shoulder and Elbow Surgery·Carlos A UquillasAndrew S Rokito
Dec 2, 2014·Clinics in Orthopedic Surgery·Chang-Wan KimDong-Gyun Kim
Nov 15, 2016·Current Pain and Headache Reports·Anita Gupta, Maimouna Bah
Sep 24, 2020·International Journal of Environmental Research and Public Health·Vincenzo CandelaVincenzo Denaro

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