Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis.

The Annals of Thoracic Surgery
Rachel EikelboomRakesh C Arora

Abstract

Postoperative atrial fibrillation (POAF) after cardiac surgery is associated with longer hospital stay and increased in-hospital death and stroke, but its long-term implications remain incompletely understood. A systematic literature review was undertaken to investigate the impact of POAF on long-term death and stroke in adult patients who undergo cardiac operations. Electronic databases (Cochrane, Embase, Ovid MEDLINE, and PubMed) were queried from inception to October 2018. Included studies compared long-term outcomes after cardiac operations in patients with and without POAF. Adjusted and unadjusted meta-analyses examined death, stroke, and major adverse cardiac and cerebrovascular events. Risk of bias was evaluated with the Newcastle-Ottawa Scale. The inclusion criteria were met by 32 studies describing 155,575 patients who had undergone cardiac operations. POAF occurred in 36,988 patients (23.7%). Meta-analysis of 10 studies (44,367 patients) demonstrated increased 1-year death in patients with POAF (odds ratio, 2.60; 95% confidence interval, 2-3.38; P < .01). Aggregate adjusted hazard of death (16 studies, n = 84,295) was also increased in patients with POAF (hazard ratio, 1.25; 95% confidence interval, 1.2-1.3; P < .01)....Continue Reading

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Citations

Sep 7, 2020·The Annals of Thoracic Surgery·Francis L Shannon
May 7, 2021·The Journal of Thoracic and Cardiovascular Surgery·Tulio CaldonazoUNKNOWN POAF-MA Group
May 5, 2021·The Journal of Thoracic and Cardiovascular Surgery·Syed T Hussain, Robert Kalimi
May 15, 2021·The Journal of Thoracic and Cardiovascular Surgery·Grace LeeStephen E Fremes
Oct 31, 2021·Journal of Cardiac Surgery·Fatih A BayraktarEbuzer Aydin

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