Postoperative bleeding risk prediction for patients undergoing colorectal surgery

Surgery
David ChenHongfang Liu

Abstract

There is limited consensus regarding risk factors for postoperative bleeding. The objective of this work was to investigate the capability of machine learning techniques in combination with practice-based longitudinal electronic medical record data for identifying potential new risk factors for postoperative bleeding and predicting patients at high risk of postoperative bleeding. A retrospective study was conducted for patients who underwent colorectal surgery 1998-2015 at a single tertiary referral center. Various predictors were extracted from electronic medical record. The outcome of interest was the occurrence of postoperative bleeding within 7 days of surgery. Logistic regression and gradient boosting machine models were trained. Area under the receiver operating curve and area under the precision recall curve were used to evaluate the performance to different models. Of 13,399 cases undergoing colorectal resection, 1,680 (12.5%) experienced postoperative bleeding. A total of 299 variables were evaluated. Logistic regression and gradient boosting machine models returned an area under the receiver operating curve of 0.735 and 0.822 and area under the precision recall curve of 0.287 and 0.423, respectively. In addition to we...Continue Reading

References

Feb 1, 1988·The American Journal of Clinical Nutrition·D T DempseyG P Buzby
Aug 1, 1988·The British Journal of Surgery·P I Tartter
Jul 6, 2000·American Journal of Surgery·S BenoistP Valleur
Jul 26, 2008·Annual Review of Psychology·John W Graham
Feb 16, 2010·Artificial Intelligence in Medicine·Dursun DelenZhenyu James Kong
Mar 27, 2010·Patient Safety in Surgery·Philipp KirchhoffDieter Hahnloser
Apr 26, 2011·International Journal of Computer Assisted Radiology and Surgery·Evangelia I ZacharakiChristos Davatzikos
Jun 29, 2011·Journal of the American Medical Informatics Association : JAMIA·Manabu ToriiHongfang Liu
Nov 1, 2011·Bioinformatics·Daniel J Stekhoven, Peter Bühlmann
Jul 4, 2012·Annals of Internal Medicine·Jeffrey L CarsonUNKNOWN Clinical Transfusion Medicine Committee of the AABB
Dec 12, 2012·Diseases of the Colon and Rectum·E ManilichF H Remzi
Apr 4, 2013·JAMA : the Journal of the American Medical Association·Travis B Murdoch, Allan S Detsky
May 28, 2013·Lancet·Lawrence T GoodnoughMichael F Murphy
May 29, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T GoldaS Biondo
Jul 25, 2013·American Journal of Surgery·Thomas N RobinsonMarc Moss
May 21, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Zhobin MoghadamyeghanehMichael J Stamos
Mar 10, 2015·Computational and Structural Biotechnology Journal·Konstantina KourouDimitrios I Fotiadis
May 29, 2015·Nature·Yann LeCunGeoffrey Hinton
Jun 17, 2015·Diagnostic and Interventional Imaging·J-P TasuS Velasco
Jan 17, 2016·American Journal of Surgery·Masayoshi YasuiUNKNOWN Clinical Study Group of Osaka University (CSGO), Colorectal Group
Jan 25, 2016·The Lancet. Psychiatry·Adam Mourad ChekroudPhilip Robert Corlett
Jul 28, 2016·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·James P MoriartyJames M Naessens
Oct 13, 2016·JAMA : the Journal of the American Medical Association·Jeffrey L CarsonAaron A R Tobian

❮ Previous
Next ❯

Citations

Apr 14, 2021·The Journal of Surgical Research·Omar ElfanagelyJohn P Fischer
Aug 30, 2021·Journal of Thrombosis and Haemostasis : JTH·Floris T M BoschNick van Es
Oct 31, 2021·Langenbeck's Archives of Surgery·Jonas HennHanno Matthaei
Jan 8, 2022·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·David Uihwan LeeRaffi Karagozian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.