Postoperative clinicopathological factors affecting cervical adenocarcinoma: Stages I-IIB

Medicine
Jiansong ZhouHanmei Lou

Abstract

Currently, cervical adenocarcinoma (ADC) receives the same standard treatment as squamous cell carcinoma, but this treatment regimen is not wholly suited for ADC. The present study was conducted to assess the prognostic role of postoperative clinicopathological factors in patients with stage I-IIB cervical ADC.The study examined 312 patients with stage I-IIB cervical ADC who underwent radical hysterectomy, including pelvic lymphadenectomy, at our institutions between October 2006 and September 2014. Overall survival (OS) and relapse-free survival (RFS) was analyzed by the Kaplan-Meier method. Sites of recurrence were classified as local and distant locations.The 5-year OS and RFS rates were 88.2% and 83.8%, respectively. The 5-year OS rates for patients with International Federation of Gynecology and Obstetrics (FIGO) stage IA, IB, IIA, and IIB were 100.0%, 90.7%, 82.8%, and 55.6%, respectively. The Cox model identified number of positive pelvic nodes and age at surgery as independent prognostic factors for survival, and number of positive pelvic nodes and postoperative tumor diameter (≥4 cm) as independent prognostic factors for relapse. Cancer recurrence developed in 35 women. The top three recurrence sites were pelvis, vagin...Continue Reading

References

Feb 15, 1995·International Journal of Radiation Oncology, Biology, Physics·C M WestR D Hunter
Apr 13, 2000·International Journal of Cancer. Journal International Du Cancer·A P VizcainoD M Parkin
Oct 4, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T IrieN Terakawa
Jan 31, 2004·Gynecologic Oncology·A BaalbergenTh J M Helmerhorst
Feb 10, 2004·Gynecologic Oncology·William T Creasman, Matthew F Kohler
Sep 21, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Freddie BrayElisabete Weiderpass
Sep 5, 2006·Vaccine·D Maxwell Parkin, Freddie Bray
Apr 30, 2009·British Journal of Cancer·T KasamatsuH Tsuda
Jul 11, 2009·Journal of Gynecologic Oncology·Kidong KimJae Weon Kim
Nov 3, 2009·Gynecologic Oncology·Lilian T GienGillian Thomas
May 18, 2010·International Journal of Cancer. Journal International Du Cancer·Lisen Arnheim DahlströmPär Sparén
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Jan 24, 2012·Gynecologic Oncology·Vijaya GalicJason D Wright
Aug 9, 2012·British Journal of Cancer·S PolterauerG Heinze
Feb 2, 2013·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Hyun Chul ChoYong-Beom Kim
Oct 25, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hiroyuki FujiwaraKeiichi Fujiwara

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BETA
hysterectomy

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