Postoperative delirium and short-term cognitive dysfunction occur more frequently in patients undergoing valve surgery with or without coronary artery bypass graft surgery compared with coronary artery bypass graft surgery alone: results of a pilot study

Journal of Cardiothoracic and Vascular Anesthesia
Judith A HudetzPaul S Pagel

Abstract

The authors tested the hypothesis that patients undergoing valve repair or replacement surgery with or without coronary artery bypass graft (CABG) surgery using cardiopulmonary bypass (CPB) had a greater incidence of postoperative delirium and cognitive dysfunction compared with patients undergoing CABG surgery alone. Prospective study. Veterans Affairs medical center. Forty-four age- and education-balanced male patients (≥ 55 years of age) undergoing elective cardiac surgery with CPB (n = 22 valve ± CABG surgery and n = 22 CABG surgery alone) and nonsurgical controls (n = 22) were recruited. None. Delirium was assessed with the Intensive Care Delirium Screening Checklist before and for 5 consecutive days after surgery. Recent verbal and nonverbal memory and executive functions were assessed using a psychometric test battery before and 1 week after cardiac surgery or at 1-week intervals in nonsurgical controls. Intensive care unit stay, hospital stay, and 30-day readmission were significantly (p = 0.03, p = 0.01, and p = 0.04, respectively) longer in patients undergoing valve surgery ± CABG surgery versus CABG surgery alone. Postoperative delirium occurred more frequently (p = 0.01) in patients undergoing valve ± CABG surgery v...Continue Reading

References

Jan 1, 1984·Soins; la revue de référence infirmière·E Guillibert
Jan 1, 1982·Journal of Psychiatric Research·J A YesavageV O Leirer
Feb 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·R E ClarkG J Magovern
Jul 1, 1994·Stroke; a Journal of Cerebral Circulation·W PugsleyS Newman
Jan 1, 1996·Journal of Cardiothoracic and Vascular Anesthesia·D A StumpS P Newman
Jul 28, 1997·The Journal of Comparative Neurology·B Pakkenberg, H J Gundersen
Oct 23, 1997·Science·J H Morrison, P R Hof
Dec 9, 1998·Journal of Clinical and Experimental Neuropsychology·C RandolphT N Chase
Jan 13, 1999·European Journal of Anaesthesiology·L S Rasmussen
Jul 15, 1999·Journal of Psychosomatic Research·R C van der MastJ D Habbema
Nov 24, 1999·British Journal of Anaesthesia·J B DijkstraJ Jolles
May 16, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·H IharaM London
May 20, 2000·Annals of the New York Academy of Sciences·V Hachinski, D Munoz
Feb 24, 2001·Acta Anaesthesiologica Scandinavica·L S RasmussenUNKNOWN ISPOCD group. The International Study of Postoperative Cognitive Dysfunction
Feb 27, 2001·BMJ : British Medical Journal·D W Wilmore, H Kehlet
Apr 21, 2001·General Hospital Psychiatry·D LitakerZ Tannous
Jun 30, 2001·Intensive Care Medicine·N BergeronY Skrobik
Aug 10, 2002·Anesthesiology·Tim JohnsonUNKNOWN ISPOCD2 Investigators
Nov 6, 2002·Journal of the Neurological Sciences·David Russell
Dec 25, 2007·Anesthesiology·Terri G MonkJoachim S Gravenstein
May 9, 2009·Acta Anaesthesiologica Scandinavica·J A HudetzD C Warltier

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Citations

Jan 5, 2011·Critical Care : the Official Journal of the Critical Care Forum·Dong-Liang MuChun-Xia Shi
Oct 9, 2013·BioMed Research International·Ieva NorkienėJūratė Šipylaitė
Apr 6, 2013·British Medical Bulletin·Susana VacasMervyn Maze
Oct 13, 2015·Journal of Cardiothoracic and Vascular Anesthesia·Alexa HollingerLuzius A Steiner
Sep 24, 2015·Journal of Cardiothoracic and Vascular Anesthesia·Lurdes TseAlasdair M Barr
Aug 21, 2013·Psychosomatics·Andreas Baranyi, Hans-Bernd Rothenhäusler
Jan 23, 2016·JACC. Cardiovascular Interventions·Masieh AbawiPieter R Stella
Jul 13, 2012·Journal of Cardiac Surgery·Yiyun LinZhinong Wang
Jun 15, 2014·Interactive Cardiovascular and Thoracic Surgery·Emaddin KidherThanos Athanasiou
May 16, 2015·Current Treatment Options in Neurology·Jose Torres, Koto Ishida
Nov 1, 2018·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Irene InstenesTone M Norekvål
Oct 9, 2019·Journal of the American Geriatrics Society·Andrew H FordOsvaldo P Almeida
Jul 19, 2017·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Jason B O'NealAndrew D Shaw
Mar 3, 2020·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Sikandar H KhanBabar A Khan
Jul 1, 2014·The Journal of Cardiovascular Nursing·Hsiu-Ching LiCheryl Chia-Hui Chen
Feb 2, 2019·Frontiers in Psychiatry·Seyed A Safavynia, Peter A Goldstein

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