PMID: 11934511Apr 6, 2002Paper

Postoperative development of children after hemispherotomy

Brain & Development
Taketoshi MaeharaMari Inoue

Abstract

We studied the postoperative development of 14 children with cortical dysgenesis who underwent modified functional hemispherectomy (hemispherotomy) at the age of 6 years or younger. At follow-up of 24-72 months (median of 47 months), six (43%) were seizure-free, six achieved>90% reduction, one achieved 50-90% reduction, and one achieved 0-50% reduction in seizure frequency. At the preoperative and final postoperative examinations, mean scores of developmental quotient (DQ) were as follows: 25.5 and 31.9 in total DQ, 26.0 and 33.7 in intellectual DQ, and 27.4 and 22.9 in motor DQ. Children scoring >50 points in preoperative intellectual DQ score obtained near-normal intellectual DQ postoperatively, while, those scoring <10 DQ preoperatively remained at a low developmental level. Among children with DQ scores in the range from 10 to 50, two children who obtained seizure-free outcome and were operated upon in the first 3 years of life achieved marked developmental progress. The present study indicated that high preoperative intellectual DQ and cessation of seizures seem to be associated with better postoperative intellectual development. However, long-term observation of postoperative development and an accumulation of more cases ...Continue Reading

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Citations

Nov 8, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Vera Cristina Terra-BustamanteAmérico Ceiki Sakamoto
Jun 22, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Shimrit Uliel-SibonyShlomi Constantini
Sep 29, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Roberto CaraballoHugo Pomata
Oct 25, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Tsukasa OhashiEiji Nakagawa
Nov 20, 2009·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Sharyl A Samargia, Teresa Jacobson Kimberley
Sep 2, 2008·Neurosurgical Focus·Sandrine De Ribaupierre, Olivier Delalande
Jan 21, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Vera C Terra-BustamanteAmérico C Sakamoto
Jul 14, 2012·Neural Plasticity·Mark W BurkeMaurice Ptito
Aug 15, 2014·Indian Journal of Pediatrics·Ajay Gupta
Feb 26, 2013·Brain & Development·Monique M J Van Schooneveld, Kees P J Braun
Jun 19, 2012·Pediatric Neurology·Kentarou NakashimaIsao Kusakawa
Aug 6, 2010·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Tsunehisa NagamoriKenji Fujieda
Jan 26, 2010·Brain and Language·Frédérique LiégeoisFaraneh Vargha-Khadem
May 20, 2008·Lancet Neurology·Susan Spencer, Linda Huh
Feb 16, 2008·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Masaya KubotaNobutaka Arai
Aug 24, 2005·Seminars in Pediatric Neurology·Deepak K Lachhwani
Feb 19, 2008·Pediatrics International : Official Journal of the Japan Pediatric Society·Yumi KonoYoko Honma
Jul 29, 2015·Seizure : the Journal of the British Epilepsy Association·Gudrun GröppelMartha Feucht
Jun 9, 2015·International Journal of Surgery·Manas PanigrahiSita Jayalakshmi
Aug 11, 2007·Seizure : the Journal of the British Epilepsy Association·D LettoriF Guzzetta
Apr 6, 2007·Seizure : the Journal of the British Epilepsy Association·N Bahi-BuissonR Nabbout
Aug 5, 2011·Seizure : the Journal of the British Epilepsy Association·Hansel M GreinerKi-Hyeong Lee
Nov 18, 2005·Brain : a Journal of Neurology·Noriko SalamonGary W Mathern
Dec 5, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Joceli Rodrigues SilvaAna Paula Hamad
Aug 12, 2017·Neurosurgical Review·Andrea BartoliK Schaller
Jul 22, 2020·World Neurosurgery·Claudia M Kuzan-FischerCaitlin E Hoffman

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