Postoperative monitoring of the oxygenation state of the graft liver in cases with hepatopulmonary syndrome

Transplantation
T KitaiA Tanaka

Abstract

Postoperative changes in the oxygen saturation of hemoglobin in the graft liver (graft SO2) were monitored by near-infrared spectroscopy in four cases complicated by hepatopulmonary syndrome. A plastic cylinder was placed in the abdominal wall, and optical measurements of the graft liver were obtained through this window. Our findings were as follows; (1) graft SO2 decreased after abdominal wall closure, and decreased further 1 day after surgery. (2) Graft SO2 was maintained despite severe hypoxemia, with partial pressure of oxygen in arterial blood as low as 50 mmHg. High hematocrit was beneficial for oxygenating the graft. (3) Graft livers could tolerate hypoxia with a graft SO2 as low as 20%. (4) It may be useful to monitor graft SO2 during the critical period after transplantation for the assessment of graft function.

References

Jan 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J K StollerW D Carey
Jun 1, 1989·American Journal of Diseases of Children·R E BokulicB P Wood
Nov 1, 1974·Microvascular Research·B ChanceL Mela
Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D H Van ThielT E Starzl
Jan 1, 1995·Transplant International : Official Journal of the European Society for Organ Transplantation·T KitaiY Yamaoka
Apr 1, 1995·Annals of Internal Medicine·P A Lange, J K Stoller
Oct 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T KitaiK Hirao

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Citations

Mar 12, 1999·The Surgical Clinics of North America·V L ScottY Kang
Jul 29, 1999·Journal of Hepatology·A E El-DesokyB R Davidson
Dec 10, 1997·Transplantation·E HatanoY Yamaoka
Oct 22, 2009·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Junichi KanekoNorihiro Kokudo

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