Postoperative nomogram for predicting disease-specific death and recurrence in papillary thyroid carcinoma

Head & Neck
Brian Hung-Hin LangKyu Eun Lee

Abstract

A nomogram could provide individualized prognostic for papillary thyroid carcinoma (PTC). The purpose of our study was to develop and validate a new nomogram. Consecutive patients with PTC from 2 different institutions were analyzed and divided into the development (n = 849) and validation (n = 275) sets. The former was used for formulating a nomogram in predicting disease-specific death and recurrence, whereas the latter was for validation (by area under the curve [AUC]). The nomogram had excellent discrimination in predicting 10-year disease-specific death and recurrence (0.984; 0.969-0.998; and 0.743; 0.658-0.828; respectively). A score <30 meant 100% of the patients survived at 10 years and those who died within 10 years had a score ≥30. A score <17 meant almost all the patients (91.04%) were disease-free within 10 years. Using a competing-risk model, a nomogram was created with excellent discriminatory ability and accuracy in predicting 10-year disease-specific death and recurrence for PTC. Our results implied its potential for wider use in other populations. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1256-E1263, 2016.

References

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Jun 27, 2007·Annals of Surgery·Brian Hung-Hin LangKing-Yin Lam
Nov 7, 2007·Nature Clinical Practice. Urology·Michael W Kattan, Peter T Scardino
Jun 23, 2009·Cancer·Karim Touijer, Peter T Scardino
Dec 28, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Limin YangNaoko Sakamoto
Mar 6, 2013·Nature Reviews. Endocrinology·Tracy S Wang, Julie A Sosa
Oct 25, 2013·The Journal of Clinical Endocrinology and Metabolism·K Alok PathakRichard W Nason
Jan 10, 2014·Endocrine-related Cancer·Brian Hung-Hin LangYeo-Kyu Youn
Feb 18, 2014·The Plant Cell·William Wing Ho Ho, Detlef Weigel
Mar 27, 2015·World Journal of Surgery·Brian Hung-Hin Lang, Carlos K H Wong

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Citations

Nov 20, 2016·Journal of Surgical Oncology·Seo Ki KimJee Soo Kim
May 18, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·I J NixonD Kim
Oct 5, 2019·International Journal of Endocrinology·Yongfeng DingLisong Teng
Dec 4, 2019·Clinical & Experimental Metastasis·Jingni HeJiapeng Yang
Oct 27, 2020·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Luigi Di FilippoMohssen Ansarin
Jul 27, 2021·International Journal of Endocrinology·Hai-Long TanShi Chang
Aug 20, 2021·JAMA Otolaryngology-- Head & Neck Surgery·Hyeonkyeong KimByung-In Moon

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