Postoperative recurrence of hepatocellular carcinoma. Two hundred five consecutive patients who underwent hepatic resection in 15 years

Archives of Surgery
M F ChenS C Chen

Abstract

To report the results of our investigation of the postoperative intrahepatic recurrent rates and the patterns of recurrence and to determine the factors that influenced these patterns of recurrence. Case series. Department of Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan. Between 1977 and 1991, 162 men and 43 women with hepatocellular carcinoma underwent hepatic resection. The surgical mortality rate was 4.4%. Of the 196 patients who were discharged from the hospital, 114 have since died and 20 were not available for follow-up. The overall cumulative recurrent rates for the last 5 years (1987 through 1991) were 59.7%, 65.0%, 76.5%, 77.0%, and 79.7%, respectively. Eighty patients experienced intrahepatic recurrence. Of these, 21 (26.2%) had recurrence near the resected stump, 43 (53.8%) had a single nodular recurrence in the remnant liver, and 16 (20%) had wide-spread multinodular recurrence. The patients with resected margins of less than 1 cm in diameter had relatively higher recurrence rates than those with resected margins of greater than 1 cm in diameter. All recurrences were noted within 3 years of the resection. The preoperative serum alpha-fetoprotein levels were directly related to the length of time to recurren...Continue Reading

Citations

Jan 4, 1998·Journal of Gastroenterology and Hepatology·M F Chen, L B Jeng
Dec 26, 2001·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·J H LimY I Kim
May 8, 2004·The Cancer Journal·Timothy M PawlikJean-Nicolas Vauthey
Feb 24, 2006·Journal of Surgical Oncology·Shao-Bin ChengFang-Ku P'eng
Jun 15, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Etonia Y-T PangNathalie Wong
Oct 16, 2007·Molecular & Cellular Proteomics : MCP·Xin YiSheung-Tat Fan
Sep 30, 2010·Journal of Evaluation in Clinical Practice·Yaojen ChangNoriaki Aoki
Mar 13, 2015·Annals of Surgical Oncology·Gaya SpolveratoTimothy M Pawlik
Jan 5, 2018·Expert Review of Gastroenterology & Hepatology·Gui-Qian HuangMing-Hua Zheng
Dec 22, 1999·The British Journal of Surgery·S TakanoS Iwai
Aug 17, 2004·The American Journal of Gastroenterology·Kuo-Shyang JengYi-Chun Tsai
Oct 7, 2008·Journal of Hepato-biliary-pancreatic Surgery·Akira KobayashiTakenari Nakata
Jan 27, 2005·The British Journal of Surgery·C-C WuF-K P'eng
Feb 28, 2007·Journal of Surgical Oncology·Koichi OishiToshimasa Asahara
May 30, 2014·International Journal of Molecular Sciences·Thomas TuNicholas A Shackel
Nov 7, 2014·Annals of Surgical Oncology·Shigeru MarubashiMasato Sakon
Nov 1, 2016·Journal of Gastroenterology and Hepatology·Eung Chang LeeSang-Jae Park
Jun 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Y IkedaK Sugimachi
Nov 27, 1998·Annals of Surgical Oncology·S I Schwartz
May 2, 1997·International Journal of Cancer. Journal International Du Cancer·S KuriyamaT Tsujii
Jul 29, 2005·The New England Journal of Medicine·Kenneth K TanabeGregory Y Lauwers
Jun 8, 2002·World Journal of Surgery·Miin-Fu ChenWei-Chen Lee
Oct 1, 2004·World Journal of Surgery·Wei-Chen LeeMiin-Fu Chen
Jun 15, 2007·Annals of Surgical Oncology·Kuniya TanakaShinji Togo

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