PMID: 6986121Jan 1, 1980Paper

Postoperative T-tube cholangiography. Is antibiotic coverage necessary

Annals of Surgery
H A PittJ L Cameron

Abstract

One hundred patients undergoing postoperative cholangiography had blood cultures drawn prior to and 15 minutes and six hours after cholangiography. Bile cultures obtained prior to cholangiography grew organisms in 92 of 100 patients with E. coli, Klebsiella pneumoniae and enterococcus being the bacteria most frequently isolated. Anaerobes were isolated from the bile in 21% of the patients. Nine of 83 patients (11%) not receiving antibiotics developed a bacteremia after cholangiography with organisms identical to those in the bile. All nine patients recovered without further complications of cholangiography. Those who developed a bactermia could not be distinguished from the group as a whole on the basis of age, sex, laboratory data, type of surgery or cholangiographic findings. None of the eight patients with negative bile cultures and none of 17 patients on antibiotics at the time of cholangiography experienced a bacteremia. Ninety to 93% of 304 organisms isolated from the bile were sensitive to a combination of a penicillin and an aminoglycoside. Most patients undergoing postoperative tube cholangiography do not develop a bacteremia and do not require antibiotics. Only patients with positive bile cultures who might tolerate a...Continue Reading

References

Jul 21, 1973·British Medical Journal·M R KeighleyJ P Kelly
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Citations

Nov 1, 1991·The British Journal of Radiology·P HollandJ Buckels
Jan 1, 1986·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·R OrdaT Wiznitzer
Sep 1, 1992·Current Problems in Surgery·S H Dougherty, R L Simmons
Aug 1, 1992·Current Problems in Surgery·S H Dougherty, R L Simmons
Dec 6, 2017·Annals of Surgery·Henry A Pitt
Dec 1, 1986·Infection Control : IC·R M Gullberg
Jan 1, 1983·Pharmacology & Therapeutics·G D Bell
Jul 1, 1982·Current Problems in Surgery·R K Tompkins, H A Pitt
Dec 1, 1982·Current Problems in Surgery·G L Jordan
Sep 1, 2009·Journal of Vascular and Interventional Radiology : JVIR·Wael E A SaadDavid L Waldman

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