Postoperative usage of tolvaptan in a patient with aortic valve stenosis complicated by Child-Pugh classification B liver cirrhosis and hepatic edema

CEN Case Reports
Yasunori IidaTakahiko Misumi

Abstract

We report the case of an 80-year-old woman with postoperative congestive heart failure (CHF) complicated by Child-Pugh classification B liver cirrhosis and hepatic edema successfully treated with tolvaptan. The patient suffered from liver cirrhosis and underwent partial hepatectomy for a hepatocellular carcinoma diagnosed together with a severe aortic valve stenosis. Aortic valve replacement was performed under cardiopulmonary bypass. The postoperative course was uneventful until CHF and hepatic edema symptoms appeared on postoperative day (POD) 2. The symptoms were treated with intravenous human atrial natriuretic peptide and oral diuretics. As the condition showed no improvement, oral tolvaptan was administered on POD 11 and thereafter, which markedly improved the symptoms. This is apparently the first report describing the effectiveness of tolvaptan for the postoperative management of fluid balance in a patient with cardiac and liver dysfunction.

References

Jun 4, 1999·The Annals of Thoracic Surgery·P BizouarnJ L Michaud
Apr 24, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Matthias ThielmannHeinz Jakob
Mar 23, 2012·Electrolyte & Blood Pressure : E & BP·Joo-Hark YiHo-Jung Kim
May 21, 2013·The Journal of International Medical Research·Isao SakaidaUNKNOWN ASCITES 14-Day Administration Study Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Related Papers

Kyobu geka. The Japanese journal of thoracic surgery
S IkenagaKimikazu Hamano
General Thoracic and Cardiovascular Surgery
Suguru WatanabeKouichi Tabayashi
Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
Masaya TakahashiKimikazu Hamano
General Thoracic and Cardiovascular Surgery
Mohammad Hassan NematiMahmood Zamirian
© 2022 Meta ULC. All rights reserved