Postoperative use of slow-release opioids: The impact of the Australian and New Zealand College of Anaesthetists/Faculty of Pain Medicine position statement on clinical practice

Anaesthesia and Intensive Care
Adeline Ch TanJonathan Penm

Abstract

Dose titration with immediate-release opioids is currently recommended for acute pain. The Australian and New Zealand College of Anaesthetists and the Faculty of Pain Medicine released a statement in March 2018 supporting their use in the treatment of opioid-naïve patients; however, the impact of this statement on clinical practice is currently unknown. This retrospective cohort study was conducted to compare opioid prescribing patterns before and after the release of the recommendations. Data were collected on 184 patients (2017, n = 78; 2018, n = 106) admitted to the Prince of Wales Hospital in November 2017 and 2018, which consisted of demographic data, opioid prescriptions and discharge opioid information. The main outcome is the number of prescriptions of slow-release opioids in 2017 versus 2018 after the recommendations were published. Confounding factors were accounted for using logistic and multiple regression as appropriate. There was a 29% decrease in slow-release opioid prescriptions during hospitalisation (n = 31, 40% versus n = 12, 11%; P < 0.001) and 17% decrease at discharge (n = 20, 26% versus n = 9, 9%; P = 0.02) post-publication. After adjusting for confounders, the odds of slow-release opioids being prescribe...Continue Reading

References

Jul 1, 1996·Journal of Clinical Pharmacology·A SunshineP D Goldenheim
Apr 24, 2001·The Journal of Bone and Joint Surgery. American Volume·A ChevilleE Narcessian
May 20, 2008·British Journal of Anaesthesia·H BreivikA Stubhaug
Apr 7, 2011·JAMA : the Journal of the American Medical Association·Nora D VolkowSusan R B Weiss
Jun 30, 2011·Indian Journal of Anaesthesia·Mohamed Daabiss
Mar 14, 2012·Archives of Internal Medicine·Asim AlamChaim M Bell
Jul 12, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Lynn R Webster
Aug 16, 2016·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Jing-Ping XiaoGuo-Jun Wang
Mar 17, 2017·MMWR. Morbidity and Mortality Weekly Report·Anuj ShahBradley C Martin
May 26, 2017·Journal of Orthopaedic Trauma·John RuderUNKNOWN PRIMUM Group
Jun 9, 2017·Obstetrics and Gynecology·Malavika PrabhuBrian T Bateman
Mar 7, 2018·Foot & Ankle International·Haley M MerrillMatthew M Buchanan
Mar 28, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·David L MurphyRichard C Dart
Aug 24, 2018·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Seshadri C MudumbaiRandall S Stafford
Apr 16, 2019·Lancet·Mark D NeumanHannah Wunsch
May 13, 2019·Journal of Biomedical Informatics·Paul A HarrisUNKNOWN REDCap Consortium

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