Abstract
To investigate the changes of inflammatory factors and hemostatic variable in plasma after a high-fat meal in normocholesterolemic patients with essential hypertension. A total of 60 hypertensive patients were randomly assigned to accept a single high-fat meal (group 1, n=40) or not (group 2, n=20) in the morning after an overnight fast, and 20 healthy participants (group 3) consumed a single high-fat meal on the same day. Plasma lipid profiles, high-sensitivity C-reactive protein (hsCRP), tumor necrosis factor alpha (TNFalpha), soluble P-selectin and plasminogen activator inhibitor type 1 (PAI-1) antigen levels were measured at fasting and 4 h after meal ingestion. Postprandial triglyceride levels increased significantly in groups 1 and 3 (P<0.01), whereas levels were higher in group 1 (P<0.001). Postprandial plasma TNFalpha, hsCRP, soluble P-selectin and PAI-1 antigen levels increased in group 1 (P<0.001) but not in group 3. Postprandial plasma triglyceride level was correlated with log(hsCRP) (P<0.001), TNFalpha (P<0.001), soluble P-selectin (P<0.01) and PAI-1 antigen (P<0.05) levels, respectively. Both postprandial plasma level of soluble P-selectin and that of PAI-1 antigen were positively and significantly correlated with...Continue Reading
References
May 1, 1991·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·P H GrootL Havekes
Nov 1, 1990·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·A Stiko-RahmJ Nilsson
May 6, 1998·Atherosclerosis·A BröijersénP Hjemdahl
Sep 11, 1998·Atherosclerosis·C D ByrneD J Grainger
May 15, 1999·Circulation Research·W DichtlJ Nilsson
Jun 18, 1999·Chronobiology International·L UndarL Undar
Aug 10, 2000·Circulation·H DoiH Yasue
Aug 30, 2000·Circulation·L M Blanco-ColioJ Egido
Sep 22, 2000·Atherosclerosis·S LopezG Nalbone
Feb 13, 2001·Atherosclerosis·R A AndersonM P Frenneaux
Nov 21, 2001·Coronary Artery Disease·S P ZhaoB Xia
Mar 30, 2002·Journal of the American College of Cardiology·Francesco NappoDario Giugliano
May 23, 2002·Clinical Cardiology·Liu LingBing Xia
Jul 18, 2002·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Dianne A HysonJohn C Rutledge
Sep 5, 2002·Circulation·Antonio CerielloEnrico Motz
Jan 29, 2003·Circulation·Sridevi DevarajIshwarlal Jialal
May 8, 2003·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Shinji MorimotoTadaaki Iwasaki
Aug 18, 2004·Circulation·Shui Ping ZhaoYu Ling Li
Oct 20, 2004·Circulation·Tarek KhreissJános G Filep
Nov 5, 2004·The Journal of Pharmacology and Experimental Therapeutics·So Youn ParkKi Whan Hong
Dec 25, 2004·Thrombosis Research·Masako YamazakiMakoto Iwata
Mar 19, 2005·Circulation Research·Radjesh J BisoendialErik S G Stroes
May 4, 2005·Circulation·Antonio CerielloDario Giugliano
Jul 28, 2005·Clinical and Experimental Immunology·A PaezF A Massó
Oct 4, 2005·Lipids in Health and Disease·Genovefa D KolovouDennis V Cokkinos
Jan 25, 2006·Journal of Molecular and Cellular Cardiology·Yao-Jen LiangLing-Ping Lai
Jul 11, 2006·British Journal of Haematology·Gil YaronDavid Varon
Jan 11, 2007·Journal of Hypertension·Santina CottoneGiovanni Cerasola
Apr 21, 2007·Circulation Research·Randall SchwartzPhilip W Shaul
May 15, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Bonnie L GoodwinDuane C Eichler
Aug 21, 2007·Nucleic Acids Research·Yong Seok ChoiSunjoo Jeong
Citations
Apr 1, 2010·Therapeutic Advances in Endocrinology and Metabolism·Mitra TavakoliRayaz A Malik
Aug 8, 2013·European Journal of Nutrition·Antonio CamargoJose Lopez-Miranda
Jul 13, 2013·Molecular Nutrition & Food Research·Mohammed Herieka, Clett Erridge
Jun 20, 2015·International Journal of Endocrinology·Katarina LalićNebojša M Lalić
Nov 13, 2012·Atherosclerosis·Ana I Perez-CaballeroJavier Delgado-Lista
Oct 1, 2011·Atherosclerosis·Kim G JacksonAnne M Minihane
Apr 4, 2017·Nutrients·Amber M MilanDavid Cameron-Smith
Jun 10, 2011·European Journal of Clinical Nutrition·M Kristensen, S Bügel
May 29, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Rob Ter HorstNiels P Riksen
Jul 23, 2013·Physiological Research·S KackovM Bilusic
Jul 6, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Emma HowardMatthew D Campbell