Postradiation segmental myoclonus selectively inhibited by REM sleep (sleep-wake myoclonus)

European Neurology
J J AskenasyP Castaigne

Abstract

A 46-year-old male patient was irradiated following left orchiectomy for seminoma. Three months after radiation, segmental myoclonus appeared involving all skeletal muscle groups up to the level of D10, the area of radiation. Urodynamic testing showed the presence of segmental myoclonus in the urethral sphincter. An around-the-clock 'continuous segmental myoclonus' during sleep and wakefulness with a frequency of 1 c/s and an amplitude of 400 microV selectively inhibited by REM sleep was not found in the literature. This continuous segmental myoclonus caused by a radiation myelopathy at D10-D11 was followed up for 2 years. It was partially controlled by carbamazepine.

Citations

May 1, 1996·Movement Disorders : Official Journal of the Movement Disorder Society·R CeravoloF Cellai
Jun 1, 1996·Italian Journal of Neurological Sciences·S BauleoG Coccagna
Mar 7, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Wolfgang N Löscher, Eugen Trinka

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