PMID: 7494334Dec 1, 1995Paper

Posttranslational signal peptidase cleavage at the flavivirus C-prM junction in vitro

Journal of Virology
C E Stocks, M Lobigs


We have investigated the cleavages at the flavivirus capsid-prM protein junction in vitro. When expressed in the absence of the flavivirus proteinase, capsid and prM, which are separated by an internal signal sequence, exist as a membrane-spanning precursor protein. Here we show the induction of posttranslational signal peptidase cleavage of prM by trypsin cleavage of a cytoplasmic region of this precursor protein.


Sep 1, 1990·Journal of Virology·F PreugschatJ H Strauss
Jan 1, 1990·Annual Review of Microbiology·T J ChambersC M Rice
Jan 1, 1987·Advances in Virus Research·E G Westaway
Apr 1, 1995·Journal of Virology·V F Yamshchikov, R W Compans
Jul 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M Lobigs

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Feb 14, 2004·Journal of Virology·Eugene V AgapovCharles M Rice
Nov 5, 2008·The Journal of Biological Chemistry·Thalia RobakisPeter Scheiffele
Apr 6, 2004·Immunology and Cell Biology·Mario LobigsEva Lee
Oct 24, 2002·Journal of Virological Methods·B C E P D OliveiraM C Cabral

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