Posttransplant survival is not diminished in heart transplant recipients bridged with implantable left ventricular assist devices

The Journal of Thoracic and Cardiovascular Surgery
Mark J RussoYoshifumi Naka

Abstract

The purpose of this study was to compare posttransplantation morbidity and mortality in orthotopic heart transplant recipients bridged to transplant with a left ventricular assist device with nonbridged recipients. To account for potential differences across device types, we stratified bridge-to-transplant recipients by type of ventricular assist device: extracorporeal (EXTRA), paracorporeal (PARA), and intracorporeal (INTRA). The United Network for Organ Sharing provided de-identified patient-level data. The study population included 10,668 orthotopic heart transplant recipients aged 18 years old or older and undergoing transplantation between January 1, 2001, and December 31, 2006. Follow-up data were provided through August 3, 2008, with a mean follow-up time of 3.17 +/- 2.15 years (range, 0-8.11 years). The primary outcome was actuarial posttransplant graft survival. Other outcomes of interest included infection, stroke, and dialysis during the transplant hospitalization; primary graft failure at 30 days; transplant hospitalization length of stay; and long-term complications including diabetes mellitus, transplant coronary artery disease, and chronic dialysis. Multivariable Cox proportional hazards regression (backward, P <...Continue Reading

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Citations

Dec 22, 2011·Computer Methods in Biomechanics and Biomedical Engineering·Andres F OsorioWilliam M DeCampli
Jul 14, 2010·Transplantation·Mark J RussoYoshifumi Naka
Aug 13, 2011·Journal of Transplantation·Arjun IyerPeter Simon Macdonald
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Jul 27, 2011·Interactive Cardiovascular and Thoracic Surgery·Marian UrbanIvan Netuka
Jun 14, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Nicholas A HaglundSimon Maltais
Dec 3, 2014·The Annals of Thoracic Surgery·Diana García SáezAndre R Simon
Oct 18, 2013·Scandinavian Cardiovascular Journal : SCJ·Tor Skibsted ClemmensenHans Eiskjær
Mar 12, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Arman KilicEric S Weiss
Jun 28, 2012·The Annals of Thoracic Surgery·Alexander IribarneMark J Russo
Mar 21, 2012·The Annals of Thoracic Surgery·George J ArnaoutakisAshish S Shah
Nov 26, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Santiago G MorenoNicola J Cooper
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Apr 9, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Ryan R DaviesChristian Pizarro
Sep 18, 2015·Cardiology in the Young·Sara K PasqualiRyan R Davies
Jan 29, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Nir UrielDonna M Mancini
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