Posttraumatic cerebral infarction: incidence, outcome, and risk factors

The Journal of Trauma
Isaac TawilThomas M Scalea

Abstract

Outcome in patients with traumatic brain injury (TBI) is often affected by secondary insults including posttraumatic cerebral infarction (PTCI). The incidence of PTCI after TBI was previously reported to be 2% with no mortality impact. We suspected that recent advances in imaging modalities and treatment might affect incidence and outcome. We sought to define the incidence and mortality impact of PTCI. We also identified risk factors associated with PTCI. We retrospectively reviewed all patients admitted between 2004 and 2006 with severe TBI (brain Abbreviated Injury Scale [AIS] score >2, Glasgow Coma Scale score [GCS] <9). Demographics, injury specifics, and clinical data were abstracted. All brain imaging studies were reviewed with an attending trauma radiologist. Statistical analysis of outcome data were performed using chi and Student's t test and multivariate analysis was performed using logistic regression to identify independent risk factors. Of the 384 patients identified with severe TBI; 93% sustained a blunt injury, 75% were men. Mortality was 21%, and 48% had a brain AIS score of 5. Mean age was 36 years (11-90 years), admission GCS score was 5 (3-8), and Injury Severity Score was 32 (9-75). Thirty-one (8%) had a con...Continue Reading

Associated Clinical Trials

References

Apr 1, 1978·Journal of Neurosurgery·L F MarshallT W Langfitt
Mar 1, 1986·Neurosurgery·M SatoC Fujii
Mar 1, 1972·Journal of Neurosurgery·C Suwanwela, N Suwanwela
Dec 1, 1984·Neurosurgery·A PasqualinR Da Pian
Feb 1, 1995·Annals of Emergency Medicine·R E BurneyR Maio
Feb 1, 1993·The Journal of Trauma·R M ChesnutM A Foulkes
Oct 30, 2004·The Journal of Trauma·Richard P DuttonThomas M Scalea
Dec 24, 2004·Current Opinion in Critical Care·Deborah M Stein, Richard P Dutton
Feb 25, 2005·The New England Journal of Medicine·Stephan A MayerUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators
Jan 19, 2006·JAMA : the Journal of the American Medical Association·Kathryn A O'ConnellM Miles Braun
Apr 20, 2006·Journal of Neurosurgery·Bizhan AarabiHoward M Eisenberg
May 5, 2006·Acta Neurochirurgica. Supplement·I TimofeevP J Hutchinson
Oct 6, 2006·Journal of Neurotrauma·Thomas S SkoglundBertil Rydenhag

❮ Previous
Next ❯

Citations

Mar 1, 2012·Journal of Neurotrauma·Deborah M SteinThomas M Scalea
Oct 23, 2008·Critical Care Medicine·David J Dries
Jun 11, 2009·The Journal of Trauma·Nicola Latronico, Rosella Marino
Mar 6, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Yong-Feng ShenLi Jiang
Jun 6, 2009·Transfusion·Jonathan MarinaroKendall P Crookston
Feb 14, 2015·Journal of Neuroscience Research·Sabrina H van IersselPhilippe G Jorens
May 7, 2016·Magnetic Resonance Imaging Clinics of North America·Wilson AltmeyerJuan Gutierrez
Feb 19, 2015·International Orthopaedics·Philipp LichteUNKNOWN Trauma Register DGU
May 7, 2014·BioMed Research International·Sabrina H van IersselViviane M Conraads
May 8, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Gang-Qun WuLi Jiang
Apr 4, 2017·Clinica Chimica Acta; International Journal of Clinical Chemistry·Ding-Bo YangLi Jiang
Feb 21, 2009·Journal of the American College of Surgeons·Deborah M SteinThomas M Scalea
Dec 23, 2017·World Journal of Surgery·Christian D WeberUNKNOWN TraumaRegister DGU
Oct 1, 2014·Korean Journal of Neurotrauma·Dong-Hyeon BaeKoang Hum Bak
Dec 24, 2015·Stroke; a Journal of Cerebral Circulation·Bart M DemaerschalkUNKNOWN American Heart Association Stroke Council and Council on Epidemiology and Prevention
Nov 7, 2009·Stroke; a Journal of Cerebral Circulation·Shyam PrabhakaranThomas P Bleck
Aug 19, 2014·Journal of Korean Neurosurgical Society·Po-Chuan ChenWen-I Liao
Dec 27, 2011·Journal of Korean Neurosurgical Society·Hyung-Yong HamJeong-Wook Choi
Feb 13, 2015·Journal of Korean Neurosurgical Society·Tae-Hoon KimJae-Won Doh
Jun 28, 2019·The Journal of Head Trauma Rehabilitation·Randolph M JenkinsWilliam C Walker
Oct 8, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Andrew D SchweitzerA John Tsiouris
Feb 6, 2020·Critical Care : the Official Journal of the Critical Care Forum·Nicola LatronicoFrancesco A Rasulo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.