Posttraumatic epilepsy and treatment.

Journal of Rehabilitation Research and Development
James W Y ChenClaude G Wasterlain

Abstract

Posttraumatic epilepsy (PTE) is a major long-term complication of traumatic brain injury (TBI). PTE usually develops within 5 years of head injury. The risk for developing PTE varies with TBI type. Both Korean and Vietnam war veterans with penetrating TBI had a 53% risk of developing PTE. The risk of developing PTE is between 10% and 25% in combat-associated closed-head trauma with positive brain imaging and about 5% in moderately severe closed-head injury without imaging finding. We do not know the risk of PTE among Operation Iraqi Freedom/Operation Enduring Freedom veterans with minimal TBI because of blast exposure.Partial seizures may manifest with subtle behavioral alterations that can be mistaken for manifestations of posttraumatic stress disorder and improperly treated. Accidents and medical complications commonly occur during seizures. Sudden unexpected death in epilepsy is most frequent among 20- to 40-year-olds. Seizures increase the likelihood of refractory seizures years after TBI. Seizures are also a social stigma that compromise veterans' reintegration into society. People with uncontrolled epilepsy are not allowed to drive and have difficulty obtaining or maintaining employment. Optimal seizure control is essenti...Continue Reading

Citations

Jul 28, 2012·Current Neurology and Neuroscience Reports·John MagnusonGeoffrey S F Ling
Jun 23, 2012·Current Treatment Options in Neurology·Christine Hung, James W Y Chen
Jun 6, 2013·Archives of Physical Medicine and Rehabilitation·John WhyteJoseph Giacino
Jan 31, 2012·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Mark B DetweilerJonna G Detweiler
Jul 22, 2010·American Journal of Physical Medicine & Rehabilitation·David X CifuBarbara Sigford
Dec 15, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jane E Risdall, David K Menon
Sep 1, 2010·Therapy·Rebecca M Verellen, Jose E Cavazos
Nov 28, 2012·Journal of the American Veterinary Medical Association·Steven G FriedenbergEdward S Cooper
Apr 28, 2012·Physical Medicine and Rehabilitation Clinics of North America·Ajit B PaiAllison Hickman
Mar 1, 2011·Neuroscience Letters·Huifang LiDavid Prince
Nov 6, 2012·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Y-Q HeC P Gyawali
May 2, 2014·Frontiers in Neurology·S Krisztian KovacsGeoffrey S F Ling
Feb 26, 2015·Journal of the Royal Army Medical Corps·Mark R CranleyE McGilloway
Oct 8, 2016·Journal of Neurosurgery. Pediatrics·Vera VigoLuca Massimi
Dec 2, 2017·Journal of Neuroscience Research·Eric J NeubergerVijayalakshmi Santhakumar
Apr 4, 2014·The Journal of Head Trauma Rehabilitation·Mary Jo V PughJordan H Grafman
Nov 18, 2010·Journal of Korean Neurosurgical Society·Seung Pil BanDae Hee Han
Dec 14, 2018·Frontiers in Neurology·M S GopalakrishnanB Indira Devi
Jul 21, 2015·Journal of Neurosurgical Anesthesiology·David TurnbullCharles Reilly
Feb 23, 2021·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Jan MračekVladimir Priban
Feb 23, 2020·World Neurosurgery·Leandro Pelegrini de AlmeidaPaulo Valdeci Worm

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