Posttraumatic stress disorder and chronic pain are associated with opioid use disorder: Results from a 2012-2013 American nationally representative survey

Drug and Alcohol Dependence
Elena BileviciusRenée El-Gabalawy

Abstract

Chronic pain conditions and posttraumatic stress disorder (PTSD) commonly co-occur and are associated with opioid use disorder (OUD). The aims of this paper were to identify prevalence estimates of OUD among individuals with and without PTSD and assess independent and combined contributions of PTSD and chronic pain conditions on OUD in a nationally representative sample. Data were extracted from 36,309 individuals from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions. Past-year PTSD and OUD were assessed using the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-5 edition. Respondents reported physician-confirmed, past-year chronic pain conditions, categorized into musculoskeletal pain (e.g., arthritis), digestive pain (e.g., pancreatitis), and nerve pain (e.g., reflex sympathetic dystrophy). We examined the weighted prevalence of OUD among those with and without PTSD. Multiple logistic regressions examined the association between PTSD and chronic pain conditions on OUD. The prevalence of OUD was higher among those with PTSD than those without. Comorbid PTSD/musculoskeletal pain and PTSD/nerve pain conditions were associated with increased odds of OUD, compared to those with n...Continue Reading

Citations

Dec 4, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Zachary T PenningtonMichael S Fanselow
Jan 4, 2020·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Elena BileviciusRenée El-Gabalawy
Jan 9, 2020·World Journal of Clinical Cases·Alicia E López-MartínezCarmen Ramírez-Maestre
Jan 14, 2021·Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Österreichischer Nervenärzte und Psychiater·Hans-Peter Kapfhammer
Jan 21, 2021·Psychiatric Services : a Journal of the American Psychiatric Association·Mayada SaadounMary Jo Larson
Jan 31, 2021·Clinical Psychology Review·Andrew H RogersGordon J G Asmundson
Mar 7, 2021·Translational Research : the Journal of Laboratory and Clinical Medicine·Marc O MartelRobert R Edwards
May 26, 2020·Dental Clinics of North America·Matthew FortinoHudson Franca
Mar 25, 2021·Journal of Evaluation in Clinical Practice·Michael MakhinsonIndra Neil Guha
Mar 11, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Hongjin LiArdith Z Doorenbos
May 11, 2021·Drug and Alcohol Dependence·Lily A BrownDwight L Evans

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