Posttraumatic stress in breast cancer survivors diagnosed at a young age

Psycho-oncology
Danny VazquezAnn H Partridge

Abstract

Young breast cancer patients experience greater psychosocial distress compared with older patients, which raises concern for their risk of posttraumatic stress disorder (PTSD). We sought to characterize the prevalence of clinically significant symptoms of PTSD and associated factors among breast cancer survivors diagnosed at a young age. The Young Women's Breast Cancer Study, an ongoing prospective cohort study, enrolled 1302 women diagnosed with breast cancer at age ≤ 40 between 2006 and 2016. Participants complete serial surveys, and we obtained additional information from medical record review. Socio-demographics, anxiety and depression, social support, and psychiatric co-morbidities and medications were assessed at study baseline (median, 5 months post-diagnosis). We defined a participant as having clinically significant posttraumatic stress symptoms (PTSS) by scoring ≥50 on the PTSD Checklist-Specific Version, administered on the 30-month survey. Among 700 women with stage 1-3 disease, the prevalence of PTSS was 6.3% (95%CI = 4.5-8.1). In multivariable analyses, PTSS was significantly associated with anxiety (OR 12.43, 95%CI = 5.81-26.59, P < .0001) and stage 2 vs 1 disease (OR 2.26, 95%CI = 1.04-4.93, P = .04). PTSS was i...Continue Reading

Associated Clinical Trials

Nov 9, 2011·Ann H. Partridge, MD, MPH

References

Jan 1, 1991·Social Science & Medicine·C D Sherbourne, A L Stewart
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
May 5, 1998·Journal of Traumatic Stress·M A Andrykowski, M J Cordova
Jan 31, 2003·Psychological Bulletin·Emily J OzerDaniel S Weiss
Nov 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Patricia A GanzJulienne E Bower
Dec 10, 2003·Seminars in Oncology·Alice B Kornblith, Jennifer Ligibel
Feb 28, 2004·Journal of Psychosomatic Research·Linda J LueckenBruce E Compas
Jun 9, 2005·Archives of General Psychiatry·Ronald C KesslerEllen E Walters
Jul 25, 2006·Pediatric Blood & Cancer·Mary T RourkeAnne E Kazak
Nov 1, 2006·Journal of Affective Disorders·M BernalUNKNOWN ESEMED/MHEDEA Investigators
Feb 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sophia K SmithElizabeth C Clipp
Mar 4, 2009·Archives of General Psychiatry·Holly C WilcoxNaomi Breslau
Apr 1, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jennifer M GierischBarbara K Rimer
Jan 3, 2012·Advances in Experimental Medicine and Biology·Kathryn J Ruddy, Ann H Partridge
Jan 25, 2012·Journal of the National Cancer Institute·Jessica Howard-AndersonAnnette L Stanton
Feb 26, 2013·Journal of the National Cancer Institute·Neomi Vin-RavivAlfred I Neugut
Jun 4, 2014·Cancer·Shoshana M RosenbergAnn H Partridge
Jan 23, 2017·The Lancet. Psychiatry·Matthew J CordovaDavid Spiegel

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