Postural control deficits in people with Multiple Sclerosis: A systematic review and meta-analysis

Gait & Posture
Laura ComberSusan Coote

Abstract

Multiple sclerosis (MS) is a neurological condition that can affect the postural stability of the individual and predispose falls in this population. A systematic literature search identified case-control studies investigating differences in postural control across a diversity of task conditions, with the exception of gait, between people with MS and healthy controls. Meta-analysis was conducted where a variable was presented by four or more studies. Forty-three studies of people with a mean Expanded Disability Status Scale (EDSS) of 1.0 to 6.0 were included. Seven conditions of assessment and 105 individual measurement variables relating to postural control were included. Quiet stance was the only condition (11 studies) possessing sufficient data to contribute to meta-analysis in terms of centre of pressure path length (SMD = 1.04, 95% CI {0.86-1.22}, p < 0.001), medio-lateral velocity (SMD = 1.35, 95% CI {0.77-1.92}, p < 0.001) and 95% confidence ellipse (SMD = 0.83 95% CI {0.59-1.08}, p < 0.001). indicate that regardless of task complexity or sensory condition, people with MS display considerable deficits in postural control in comparison to healthy controls. The large number of variables and lack of standardisation of repor...Continue Reading

Citations

Feb 10, 2019·PM & R : the Journal of Injury, Function, and Rehabilitation·Denise AnastasiDavide Cattaneo
Nov 26, 2019·Physiotherapy Canada. Physiothérapie Canada·Kirsten PotterAshley Wooldridge
Mar 17, 2020·Frontiers in Neurology·Hernan InojosaTjalf Ziemssen
Sep 12, 2019·Frontiers in Neurology·Ludivine Chamard WitkowskiGrant Handrigan
Aug 29, 2020·Journal of Foot and Ankle Research·Minna StoltHelena Leino-Kilpi
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Jun 9, 2020·Neurorehabilitation and Neural Repair·Mohamed Suhair Bin Mohamed SuhaimyStephen R Lord
Dec 12, 2020·Gait & Posture·Katherine L Hsieh, Jacob J Sosnoff
Feb 11, 2021·Motor Control·Nathan MorelliMatthew C Hoch
Feb 5, 2021·Multiple Sclerosis and Related Disorders·Nathan Morelli, Haley Morelli
Jan 12, 2021·International Journal of MS Care·Susan CooteHilary Gunn
Sep 27, 2020·Gait & Posture·Anne-Violette Bruyneel, Noémie C Duclos
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Jun 18, 2021·Physiotherapy Theory and Practice·Fatih SokeArzu Guclu-Gunduz
Aug 22, 2021·Clinical Biomechanics·Charles Van LiewDaniel S Peterson

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