PMID: 9160455May 1, 1997Paper

Postural hypotension and abnormalities of salt and water metabolism in myelopathy patients

Spinal Cord
J H Frisbie, D J Steele

Abstract

To describe the clinical manifestations of postural hypotension (PH) in myelopathy patients a standardized interview and chart review were carried out. Of 232 myelopathy patients with more than 2 years of paralysis seen during a 2 year period, 30 had been treated for PH. All PH patients were paralysed at levels higher than thoracic 7. The highest risk patients were tetraplegic, motor complete, 24 of 73 (33%). The common symptoms of PH were those of reduced consciousness (100%), strength (75%), vision (56%) and breath (53%). Precipitating factors were hot weather (77%) bowel care (33%) and meals (30%). Symptoms worsened with the duration of paralysis in 12 patients. Chronic hyponatremia was found in 54% of the PH patients and 16% of those without, P < 0.001. Of five PH-hyponatremic patients with urine sodium and osmolality determinations, five continued to retain water (> 150 mOsm/kg) while four failed to conserve salt (> 19 mmol Na/L). PH is common among myelopathy patients with higher levels of paralysis, symptoms are variable, and abnormal salt and water metabolism often coexist.

Citations

Nov 20, 2009·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Hisayoshi OgataKimitaka Nakazawa
Jul 23, 2003·Pharmacology, Biochemistry, and Behavior·Roy J MathewRobin Davis
Dec 23, 2006·Journal of Neurotrauma·Victoria E Claydon, Andrei V Krassioukov
Mar 29, 2006·Spinal Cord·J H Frisbie
Aug 18, 2009·Respiratory Physiology & Neurobiology·Andrei Krassioukov
May 2, 2009·Archives of Physical Medicine and Rehabilitation·Andrei KrassioukovUNKNOWN Spinal Cord Injury Rehabilitation Evidence Research Team
May 13, 2015·Journal of Neurotrauma·Aaron A Phillips, Andrei V Krassioukov
Oct 7, 2008·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Lorne ChiMilos R Popovic
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Jan 25, 2017·The Journal of Spinal Cord Medicine·Eva Canosa-HermidaJosé Ramón Vizoso-Hermida
Oct 3, 2018·PM & R : the Journal of Injury, Function, and Rehabilitation·Zoe K SarafisAndrei V Krassioukov
Aug 8, 2020·Topics in Spinal Cord Injury Rehabilitation·Andrei KrassioukovLisa A Beck
May 20, 2020·Spinal Cord Series and Cases·Michael Stillman, Steve Williams
Jul 18, 2020·Global Spine Journal·Edward Tien-En OngJacob Yoong-Leong Oh
Jan 18, 2018·Topics in Spinal Cord Injury Rehabilitation·Ross Davidson, Aaron Phillips
Nov 17, 2020·Topics in Spinal Cord Injury Rehabilitation·James MilliganJeremy Howcroft

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