PMID: 3718793Jun 1, 1986Paper

Potassium exchange in the human heart during atrial pacing and myocardial ischaemia

British Heart Journal
S C Webb, P A Poole-Wilson

Abstract

Potassium homoeostasis in the heart was studied during atrial pacing in 20 patients undergoing diagnostic coronary angiography. The potassium concentrations in the coronary sinus and a systemic artery were recorded continuously by means of catheter tip potassium electrodes. Ten patients with coronary artery disease and a positive exercise test developed chest pain and ST segment depression on the electrocardiogram during atrial pacing. Potassium concentrations in the coronary sinus rose initially and increased further when myocardial ischaemia developed. Ten patients including five with normal coronary arteries remained symptom free during atrial pacing with no electrocardiographic changes. In these patients coronary sinus potassium concentration increased at the onset of pacing, but returned to near control values despite continued pacing. In both groups arterial potassium concentration remained constant. Immediately after the end of pacing there was an abrupt transient fall in potassium concentrations in the coronary sinus to below control values. These results indicate that in man, as in other species, an increase in heart rate causes the transient movement of potassium out of the cell into the extracellular space. The onset...Continue Reading

References

Mar 1, 1979·The American Journal of Cardiology·A P SelwynG Forse
Aug 1, 1983·British Heart Journal·S C WebbP A Poole-Wilson
May 1, 1984·Journal of Molecular and Cellular Cardiology·A G Kléber
Jul 1, 1982·The Journal of Physiology·G Martin, M Morad
Jul 1, 1981·Journal of Molecular and Cellular Cardiology·J Weiss, K I Shine
May 1, 1980·Journal of Medical Engineering & Technology·S M Cobbe, P A Poole-Wilson
May 1, 1956·The American Journal of Physiology·D LAURENTL N KATZ

Citations

Nov 1, 1993·Cardiovascular Drugs and Therapy·Christer Sylvén
Dec 1, 1989·Journal of Molecular and Cellular Cardiology·G AksnesA Ilebekk
Nov 15, 1991·Journal of the American College of Cardiology·P NihoyannopoulosA Maseri
Mar 26, 1999·Journal of the American College of Cardiology·H E BøtkerF Andreasen
Jun 29, 2000·Scandinavian Cardiovascular Journal : SCJ·K Ylitalo, K Peuhkurinen
Jun 11, 2020·Pacing and Clinical Electrophysiology : PACE·Piotr NiewinskiPiotr Ponikowski
Oct 4, 2000·Physiological Reviews·O M Sejersted, G Sjøgaard

Related Concepts

Cardiac Pacing, Artificial
Coronary Heart Disease
Electrocardiographic Recorders
Heart
Myocardium
Potassium

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