Potency testing of cannabinoids by liquid and supercritical fluid chromatography: Where we are, what we need.

Journal of Chromatography. a
Simona FellettiMartina Catani

Abstract

Hemp and cannabis industry is undergoing a renewed interest due to legalization of marijuana (a topic that all countries are discussing, especially in recent years) and the growing importance of therapeutic properties of cannabinoids. Together with an increment in the production of hemp and recreational cannabis, there has been an increasing demand for accurate potency testing of products (i.e. quantification of main cannabinoids present in the plant in terms of weight percentage) prior commercialization. This translates in an urgent need of reliable analytical methods to characterize cannabis and hemp samples. Cannabis and hemp preparations are commercialized under various forms (e.g., flowers, oils, candies or even baked goods) usually containing a large number of often very similar compounds making their separation very challenging. Strictly connected to this, another emerging topic concerns the need for the developing of large scale separation techniques for the purification of cannabinoids from complex matrices and for the preparation of analytical-grade standards (including the chiral ones). This paper reviews the most recent achievements in both these aspects. Cutting-edge applications and novel opportunities in potency ...Continue Reading

References

Oct 1, 1978·Journal of Medicinal Chemistry·H YoshimuraS Ueki
Mar 1, 1980·Journal of Natural Products·C E TurnerE G Boeren
Jan 11, 2001·Drugs·E M Williamson, F J Evans
May 1, 2004·Phytochemical Analysis : PCA·Tri J Raharjo, Robert Verpoorte
Mar 1, 2005·Forensic Science International : Synergy·Franz E DussyThomas A Briellmann
Oct 4, 2005·Life Sciences·Mahmoud A Elsohly, Desmond Slade
Feb 2, 2010·Journal of Chromatography. a·Fabrice GrittiGeorges Guiochon
Jan 25, 2011·Current Medicinal Chemistry·G AppendinoO Taglialatela-Scafati
Feb 22, 2011·Drug Testing and Analysis·Simon Hudson, John Ramsey
Mar 1, 2011·Journal of Chromatography. a·Georges Guiochon, Fabrice Gritti
Sep 29, 2011·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Ariane WohlfarthVolker Auwärter
Jul 10, 2014·Forensic Science International : Synergy·Lars AmbachWerner Bernhard
May 5, 2016·International Journal of Analytical Chemistry·Raffaella Preti
Aug 17, 2016·Analytical Chemistry·M Farooq WahabDaniel W Armstrong
Oct 11, 2016·Natural Product Reports·Lumír Ondřej HanušGiovanni Appendino
Feb 25, 2017·Analytical and Bioanalytical Chemistry·Elizabeth M MudgePaula N Brown
Jun 24, 2017·Journal of Pharmaceutical and Biomedical Analysis·Cinzia CittiGiuseppe Cannazza
Aug 26, 2017·Journal of Pharmaceutical and Biomedical Analysis·Bhupendra PatelZhihua Tina Fan
Oct 8, 2017·Journal of Separation Science·Allegra LeghissaKevin A Schug
Nov 29, 2017·Journal of Pharmaceutical and Biomedical Analysis·Cinzia CittiGiuseppe Cannazza
Jun 25, 2018·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Hugues JamboPhilippe Hubert
Oct 24, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Omar H IsmailMartina Catani
Jan 24, 2019·European Archives of Psychiatry and Clinical Neuroscience·Suman ChandraMahmoud A ElSohly
Apr 19, 2019·ACS Medicinal Chemistry Letters·Michele ProttiLaura Mercolini
Jun 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mara MandrioliTullia Gallina Toschi
Oct 2, 2019·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Roger HudsonSteven R Laviolette

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
The Medical Letter on Drugs and Therapeutics
The Medical Letter on Drugs and Therapeutics
Forschende Komplementärmedizin
F Grotenhermen, R Saller
International Journal of Medical Sciences
Esther PapaseitMagí Farré
© 2021 Meta ULC. All rights reserved