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Potent GnRH agonists containing L-amino acid derivatives in the six position

Biochemical and Biophysical Research Communications

May 14, 1987

János SeprodiSándor Vigh

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Abstract

New agonists related to gonadotropin-releasing hormone (GnRH) have been synthesized that are comparable in potency to the GnRH and its superagonists for release of LH and estrus suppression without substitutions with D- or unnatural amino acids in position 6. We now report a series of L...read more

Mentioned in this Paper

Amino Acid [EPC]
Analogs & derivatives
Recombinant Gonadorelin
Analog
Gonadorelin Hydrochloride
GNRH1 gene
Luteozyman
Agonists
Metazoa
Amino acid derivative
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Potent GnRH agonists containing L-amino acid derivatives in the six position

Biochemical and Biophysical Research Communications

May 14, 1987

János SeprodiSándor Vigh

PMID: 3555499

DOI: 10.1016/0006-291x(87)91440-9

Abstract

New agonists related to gonadotropin-releasing hormone (GnRH) have been synthesized that are comparable in potency to the GnRH and its superagonists for release of LH and estrus suppression without substitutions with D- or unnatural amino acids in position 6. We now report a series of L...read more

Mentioned in this Paper

Amino Acid [EPC]
Analogs & derivatives
Recombinant Gonadorelin
Analog
Gonadorelin Hydrochloride

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