Potential benefits, limitations and target product-profiles of odor-baited mosquito traps for malaria control in Africa.

PloS One
Fredros O OkumuGerry F Killeen

Abstract

Traps baited with synthetic human odors have been proposed as suitable technologies for controlling malaria and other mosquito-borne diseases. We investigated the potential benefits of such traps for preventing malaria transmission in Africa and the essential characteristics that they should possess so as to be effective. An existing mathematical model was reformulated to distinguish availability of hosts for attack by mosquitoes from availability of blood per se. This adaptation allowed the effects of pseudo-hosts such as odor-baited mosquito traps, which do not yield blood but which can nonetheless be attacked by the mosquitoes, to be simulated considering communities consisting of users and non-users of insecticide-treated nets (ITNs), currently the primary malaria prevention method. We determined that malaria transmission declines as trap coverage (proportion of total availability of all hosts and pseudo hosts that traps constitute) increases. If the traps are more attractive than humans and are located in areas where mosquitoes are most abundant, 20-130 traps per 1000 people would be sufficient to match the impact of 50% community-wide ITN coverage. If such traps are used to complement ITNs, malaria transmission can be red...Continue Reading

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Mar 29, 2014·Malaria Journal·David J MengerWillem Takken
Jan 5, 2012·PloS One·Niels O VerhulstRenate C Smallegange
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Apr 30, 2015·PloS One·David J MengerWillem Takken
Mar 12, 2020·Malaria Journal·John P MasaluFredros O Okumu

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