Potential Biomolecules and Current Treatment Technologies for Diabetic Foot Ulcer: An Overview

Current Diabetes Reviews
Zenith KhashimKathiravan Krishnan

Abstract

Diabetic foot ulceration remains a major challenge and is one of the most expensive and leading causes of major and minor amputations among patients with diabetic foot ulcer. Hence the purpose of this review is to emphasize on potential molecular markers involved in diabetic foot ulcer physiology, the efficacy of different types of dressing materials, adjunct therapy and newer therapeutic approach like nanoparticles for the treatment of diabetic foot ulcer. We conducted a systematic literature review search by using Pubmed and other web searches. The quality evidence of diabetic foot ulcer biomolecules and treatments was collected, summarized and compared with other studies. The present investigation suggested that impaired wound healing in diabetic patients is an influence of several factors. All the advanced therapies and foot ulcer dressing materials are not suitable for all types of diabetic foot ulcers, however more prospective follow ups and in vivo and in vitro studies are needed to draw certain conclusion. Several critical wound biomolecules have been identified and are in need to be investigated in diabetic foot ulcers. The application of biocompatible nanoparticles holds a promising approach for designing dressing mat...Continue Reading

References

Dec 1, 1992·Burns : Journal of the International Society for Burn Injuries·O DamourC Collombel
Jan 1, 1990·Journal of Pediatric Surgery·P J HennesseyR J Andrassy
Jan 1, 1995·Annual Review of Physiology·O W Griffith, D J Stuehr
Feb 1, 1996·Diabetic Medicine : a Journal of the British Diabetic Association·A J JaapJ E Tooke
Apr 16, 1998·The Journal of Clinical Investigation·K YamasakiT R Billiar
Oct 20, 1998·American Journal of Surgery·E K LeGrand
Dec 4, 1998·American Journal of Infection Control·J B WrightR E Burrell
May 26, 1999·The Journal of Burn Care & Rehabilitation·H Q YinR E Burrell
Nov 17, 1999·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·J M SmiellB H Schwab
Jul 8, 2000·The Journal of Investigative Dermatology·G LauerS A Eming
Mar 14, 2002·Nitric Oxide : Biology and Chemistry·Birgit StallmeyerStefan Frank
May 2, 2002·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Glenn P LadwigGregory S Schultz
May 10, 2002·Journal of Wound Care·A B G Lansdown
May 22, 2002·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S BeckerJ E Gallagher
Oct 16, 2002·The International Journal of Biochemistry & Cell Biology·Breda CullenNicholas D Light
May 27, 2003·Diabetes Care·Man Wo TsangEdward K H Lam
Jun 6, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A AbidiaP T McCollum
Jan 1, 2004·Progress in Brain Research·Luigi Aloe
Mar 17, 2004·Current Opinion in Infectious Diseases·Ruth Edwards, Keith G Harding
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J R HiltonK G Harding
Oct 27, 2004·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·S GeneriniL Aloe
Nov 25, 2004·Diabetes·Sergiu-Bogdan CatrinaLorenz Poellinger
Feb 25, 2005·Vitamins and Hormones·Amy W Rachfal, David R Brigstock
May 3, 2005·Cytokine & Growth Factor Reviews·Marco PrestaMarco Rusnati
Sep 17, 2005·Journal of Materials Science. Materials in Medicine·Yanzhong ZhangZheng-Ming Huang
Nov 18, 2005·Lancet·David G ArmstrongUNKNOWN Diabetic Foot Study Consortium
Nov 18, 2005·Lancet·Vincent Falanga
Jan 6, 2006·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Stuart K BislandShane Burch
Mar 23, 2006·Journal of Leukocyte Biology·Andrej KhandogaFritz Krombach
Apr 4, 2006·Tissue Engineering·Ramalingam Murugan, Seeram Ramakrishna

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