Potential contribution of bilateral magnetic source imaging to the evaluation of epilepsy surgery candidates

Neurosurgery
M AungE C Hirschkoff

Abstract

The current procedures that are used to evaluate candidates for epilepsy surgery are time-consuming, costly, and often invasive. Magnetic source imaging (MSI), the combination of magnetoencephalography and anatomic imaging modalities, has shown promise as an efficient noninvasive means of localizing and characterizing seizure sources for possible resection. However, MSI has been limited by the inability to conduct simultaneous bilateral monitoring. In this study, a newly developed dual-magnetometer system was employed to record bilaterally the interictal activity in 30 candidates for epilepsy surgery. A standard monitoring protocol that included concurrent electroencephalographic recording and required a 2- to 3-hour examination period for each patient was developed. As a first step in a series of studies, the resultant MSI indications were compared with the information available from standard magnetic resonance imaging and concurrent electroencephalographic results. In 83% of the cases, this MSI protocol provided new information about the location of interictal epileptic activity that could be directive for subsequent patient care. Based on these results, it seems that MSI may become a cost-effective early step in epilepsy sur...Continue Reading

References

Feb 1, 1991·Brain : a Journal of Neurology·T KandaH Tanabe
Oct 16, 1987·Science·D F RoseS Sato
Sep 1, 1987·Annals of Neurology·D F RoseB Jabbari
Feb 1, 1994·Electroencephalography and Clinical Neurophysiology·C C GallenF E Bloom
May 1, 1994·Neurology·G D JacksonD G Gadian
Dec 1, 1993·Radiology·C R Jack
Jan 1, 1993·Acta Oncologica·K J Kairemo
Aug 1, 1993·Neurosurgery·C C GallenF E Bloom
Jul 1, 1993·European Journal of Nuclear Medicine·N P RowellV R McCready
Jan 1, 1993·Cancer Treatment Reviews·P J Loehrer

❮ Previous
Next ❯

Citations

Sep 13, 2002·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Maeike ZijlmansAlexander C Van Huffelen
Oct 8, 2003·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Frans S S LeijtenAlexander C Van Huffelen
Nov 24, 1999·Epilepsia·H Silfvenius
Aug 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·H StefanI Blümcke
Sep 8, 2012·Epilepsy Research and Treatment·Manouchehr Javidan
Dec 24, 2002·Seizure : the Journal of the British Epilepsy Association·Carlos AmoTomás Ortiz
Jan 1, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·J A Muñoz-YuntaC Dürsteler
May 3, 2001·Journal of Child Neurology·H Otsubo, O C Snead
Jul 16, 2011·Epilepsia·Michael E FunkeJeffrey David Lewine
Nov 7, 2017·Brain : a Journal of Neurology·Joshua Bear, Heidi Kirsch

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.