Abstract
Obesity alters whole body kinematics and joint kinetics during activities of daily living which are thought to contribute to increased risk of musculoskeletal injury, development of lower extremity joint osteoarthritis (OA), and physical disability. To date, it has widely been accepted that excess adipose tissue mass is the major driver of biomechanical alterations in obesity. However, it is well established that obesity is a systemic disease affecting numerous, if not all, organ systems of the body. Indeed, obesity elicits numerous adaptations within skeletal muscle, including alterations in muscle structure (ex. myofiber size, architecture, lipid accumulation, and fiber type), recruitment patterns, and contractile function (ex. force production, power production, and fatigue) which may influence kinematics and joint kinetics. This review discusses the specific adaptations of skeletal muscle to obesity, potential mechanisms underlying these adaptations, and how these adaptations may affect biomechanics.
Citations
Jul 8, 2018·The Journal of Experimental Biology·Jason TallisFrank Seebacher
Jan 20, 2019·The Journal of Experimental Biology·Rudolf J Schilder, Hannah Stewart
Jan 11, 2019·Medicine and Science in Sports and Exercise·Michael N VakulaDerek N Pamukoff
Jun 13, 2019·European Journal of Applied Physiology·Filippo VaccariStefano Lazzer
Apr 23, 2020·Journal of Clinical Medicine·Robinson Ramírez-VélezMikel Izquierdo
Jun 23, 2019·GeroScience·Christy S CarterLaDora Thompson
Oct 4, 2019·Journal of Applied Physiology·Frank Seebacher, Rob S James
Sep 17, 2020·Medicine and Science in Sports and Exercise·Derek N PamukoffDaniela A Rubin
Sep 19, 2019·Nutrition Reviews·Adrienne R Herrenbruck, Lance M Bollinger
Dec 17, 2019·Dose-response : a Publication of International Hormesis Society·Cintia Renata Sousa-GonçalvesAlessandro Sartorio
Sep 17, 2020·Physical Therapy·Lance M Bollinger, Amanda L Ransom
Dec 10, 2020·Journal of Sport and Health Science·Amanda Schenatto FerreiraDanilo de Oliveira Silva
Feb 3, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Valentina MuolloSilvia Pogliaghi
Mar 24, 2021·Clinical Biomechanics·Nicola A MaffiulettiAlessandro Sartorio
Apr 4, 2021·Biomolecules·Jason TallisCameron Hill
May 1, 2021·Sensors·Amaranta Orejel BustosClaudia Giacomozzi
May 12, 2021·Applied Ergonomics·Brittany D BulbrookClark R Dickerson
May 16, 2021·Aging Clinical and Experimental Research·Valentina MuolloAndrea Petronio Rossi
May 25, 2021·European Journal of Internal Medicine·Jean-Michel OppertCécile Ciangura
Jun 27, 2021·BMC Musculoskeletal Disorders·Rafael Ratti FenatoAna Tereza Bittencourt Guimarães
Nov 25, 2018·Physiology & Behavior·Luiz Fernando Farias-JuniorEduardo Caldas Costa
Mar 4, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Sharn ShelleyJason Tallis
Jun 18, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Ian C SmithWalter Herzog
Mar 29, 2020·Journal of Strength and Conditioning Research·Alice BellichaPierre Portero