Potential for misclassification of micronutrient status in children participating in a Head Start program

Journal of the American Dietetic Association
Elizabeth A DrokeLaura Hubbs-Tait

Abstract

To evaluate relations among measures of iron and zinc status, C-reactive protein (CRP), and leukocytes in low-income children participating in the Head Start program. Cross-sectional correlational study with samples collected at Head Start centers in May 2003. Forty-seven children (aged 3 to 5 years) attending Head Start centers in three rural communities. Zinc, ferritin, CRP, and complete blood count were analyzed in nonfasting blood samples. Correlations were computed among leukocyte levels, CRP levels, and measures of micronutrient status. Children having two abnormal measures (ie, leukocytes and CRP) were compared by univariate analysis of variance with children having zero or one abnormal measure. Most (72%) of the children had elevated CRP levels. Four percent were anemic (hemoglobin<11.0 g/dL [<110 g/L]); 11% had low iron stores (serum ferritin<or=15 ng/mL [<or=33.7 pmol/L]); and 77% had low iron stores when a reference value that accounts for the presence of infection was used (serum ferritin<or=30 ng/mL [<or=67.4 pmol/L]). Twenty-one percent had low plasma zinc levels. Children with two measures that indicated infection had higher serum ferritin and lower plasma zinc levels than children with zero or one indicator of i...Continue Reading

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Citations

Feb 23, 2012·Biological Trace Element Research·Vinh Q BuiReynaldo Martorell
Mar 10, 2009·Developmental Neuropsychology·Laura Hubbs-TaitBarbara J Stoecker
Sep 12, 2009·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·S EvansA MacDonald
Aug 1, 2015·Tropical Medicine & International Health : TM & IH·Ann M BuchananJohn A Crump
Mar 1, 2006·Journal of the American Dietetic Association·Keecha Harris
May 10, 2013·Critical Reviews in Clinical Laboratory Sciences·Julie L V ShawKhosrow Adeli
Mar 17, 2015·Water Research·Arun Subramani, Joseph G Jacangelo
Jan 2, 2007·Journal of the American Dietetic Association·Laura Hubbs-TaitJill R Parker

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