Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study.

The Lancet Global Health
Alexandra B HoganTimothy B Hallett

Abstract

COVID-19 has the potential to cause substantial disruptions to health services, due to cases overburdening the health system or response measures limiting usual programmatic activities. We aimed to quantify the extent to which disruptions to services for HIV, tuberculosis, and malaria in low-income and middle-income countries with high burdens of these diseases could lead to additional loss of life over the next 5 years. Assuming a basic reproduction number of 3·0, we constructed four scenarios for possible responses to the COVID-19 pandemic: no action, mitigation for 6 months, suppression for 2 months, or suppression for 1 year. We used established transmission models of HIV, tuberculosis, and malaria to estimate the additional impact on health that could be caused in selected settings, either due to COVID-19 interventions limiting activities, or due to the high demand on the health system due to the COVID-19 pandemic. In high-burden settings, deaths due to HIV, tuberculosis, and malaria over 5 years could increase by up to 10%, 20%, and 36%, respectively, compared with if there was no COVID-19 pandemic. The greatest impact on HIV was estimated to be from interruption to antiretroviral therapy, which could occur during a perio...Continue Reading

References

May 20, 2015·Lancet·Margaret E KrukBernice T Dahn
Mar 25, 2019·The Lancet Global Health·Juan F VesgaNimalan Arinaminpathy
Apr 3, 2020·The Lancet Infectious Diseases·Robert VerityNeil M Ferguson

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Citations

Aug 25, 2020·Health Policy and Planning·Amyn A MalikHamidah Hussain
Aug 14, 2020·American Journal of Physiology. Lung Cellular and Molecular Physiology·Kwun M FongUNKNOWN Forum of International Respiratory Societies (FIRS)
Sep 12, 2020·Nature Reviews. Microbiology·Emmanuel MargolinEdward P Rybicki
Sep 10, 2020·Tropical Medicine and Infectious Disease·Francesco Di GennaroGiovanni Putoto
Jul 30, 2020·Tropical Medicine and Infectious Disease·Kefyalew Addis AleneArchie C A Clements
Aug 10, 2020·Nature Medicine·Ellie Sherrard-SmithThomas S Churcher
Aug 25, 2020·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Om Prakash Yadava
Sep 3, 2020·The American Journal of Tropical Medicine and Hygiene·Alexander W KayAnna M Mandalakas
Sep 15, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Navisha DookieKogieleum Naidoo
Nov 10, 2020·Current Opinion in HIV and AIDS·Rowena Johnston
Dec 22, 2020·AIDS Patient Care and STDs·Rowena Johnston
Jan 13, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Eric P F ChowChristopher K Fairley
Jan 14, 2021·Transactions of the Royal Society of Tropical Medicine and Hygiene·Zachary Barnett-HowellAhmed Mushfiq Mobarak
Dec 15, 2020·American Journal of Ophthalmology·Lawson UngJames Chodosh
Nov 14, 2020·The European Respiratory Journal·Vladyslav NikolayevskyyDaniela Cirillo
Nov 14, 2020·Current Opinion in HIV and AIDS·Lillian B BrownMonica Gandhi
Jan 9, 2021·Infectious Diseases of Poverty·Benyun ShiJiming Liu
Feb 16, 2021·The Lancet Infectious Diseases·Seth C InzauleJohn N Nkengasong
Sep 27, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Solomon MukwenhaGodfrey Musuka
Nov 17, 2020·Development = Développement = Desarrollo·Gianni Tognoni, Alejandro Macchia
Feb 13, 2021·BMC Health Services Research·Mohsen Ghaffari DarabZahra Kavosi
Dec 20, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Giovanni GuaraldiJeffrey V Lazarus
Feb 23, 2021·Health Care for Women International·Rajani SureshSaurabh Kumar
Feb 12, 2021·Journal of Medical Virology·Daniel Rojas-BolivarMoises A Huaman
Feb 27, 2021·Journal of Medical Ethics·Thana Cristina de Campos-Rudinsky, Eduardo Undurraga
Mar 12, 2021·Transactions of the Royal Society of Tropical Medicine and Hygiene·T Déirdre HollingsworthSake J de Vlas
Mar 12, 2021·Transactions of the Royal Society of Tropical Medicine and Hygiene·Julius Patrick FerrerJuan A Solon
Mar 7, 2021·Mayo Clinic Proceedings·Gifty ImmanuelRahul Kashyap
Mar 9, 2021·Microbes and Infection·Kai J RogersNoah S Butler
Mar 14, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Richard KockAlimuddin Zumla
Mar 16, 2021·Frontiers in Cellular and Infection Microbiology·Dilara Kiran, Randall J Basaraba
Mar 26, 2021·MMWR. Morbidity and Mortality Weekly Report·Rena FukunagaTereza Kasaeva

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