Potential impact of therapeutic warfarin treatment on type II endoleaks and sac shrinkage rates on midterm follow-up examination

Journal of Vascular Surgery
Ronald M FairmanOmaida C Velazquez

Abstract

Successful endovascular aortic aneurysm repair depends on exclusion and spontaneous thrombosis of the aneurysm sac. The need for chronic postoperative anticoagulation therapy could limit the applicability of this technology with delay or prevention of sac thrombosis resulting in endoleak formation and altered remodeling of the aneurysm sac. The purpose of this study was the determination of whether chronic therapeutic anticoagulation therapy with warfarin was associated with an increased incidence rate of early or delayed postoperative endoleaks or altered rates of reduction in aneurysm sac maximum diameter. Two hundred thirty-two consecutive patients underwent abdominal aortic endografting during a 32-month period. The data were recorded prospectively with a current mean follow-up period of 18 months. The patients with endoleaks identified with 30-day postoperative computed tomographic scan angiograms subsequently underwent selective arteriography to characterize the source. The patients who underwent chronic warfarin therapy that resulted in a therapeutic internationalized normalized ratio comprised the study group. The control group was defined as all the patients with healthy coagulation profiles. Thirty-six patients (15%) ...Continue Reading

References

Nov 1, 1996·Journal of Vascular Surgery·M ResnikoffD M Shah
Jul 31, 1998·Journal of Vascular Surgery·G B TorselloT Umscheid
Jan 23, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M P ArmonB R Hopkinson
Jul 6, 2000·Journal of Vascular Surgery·Y G WolfC K Zarins
Feb 15, 2001·Journal of Vascular Surgery·M S Makaroun

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Citations

Nov 17, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Naoki FujimuraYuko Kitagawa
Sep 30, 2003·Journal of Vascular and Interventional Radiology : JVIR·Richard A BaumJeffrey P Carpenter
Aug 7, 2007·Journal of Vascular and Interventional Radiology : JVIR·Wataru HigashiuraShona Bathurst
Apr 18, 2006·Journal of Vascular Surgery·Ronald M FairmanUNKNOWN Zenith Investigators
Jan 23, 2014·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P De RangoP Cao
Sep 6, 2014·Cardiovascular and Interventional Radiology·Raymond Chung, Robert A Morgan
Feb 27, 2007·Journal of Vascular Surgery·Vikram S IyerOren K Steinmetz
Sep 5, 2006·Journal of Vascular Surgery·Daniel SilverbergMichael L Marin
Dec 4, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·R J HinchliffeUNKNOWN Zenith Users Group
Feb 8, 2014·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Miltos K LazaridesGeorge Trellopoulos
Feb 11, 2003·Vascular and Endovascular Surgery·Thomas S Maldonado, Paul J Gagne
Aug 19, 2009·Cardiovascular and Interventional Radiology·Terhi NevalaJukka Perälä
Oct 19, 2011·Cardiovascular and Interventional Radiology·Seth Klein, Daniel Picus
Feb 3, 2005·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Matthias BieblRicardo Paz-Fumagalli
May 2, 2012·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Katherine A GallagherJohn K Karwowski
Aug 2, 2013·Cardiovascular and Interventional Radiology·Minhaj S KhajaAlan H Matsumoto

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