POTENTIAL PREVENTIVE EFFECT OF LACTOBACILLUS ACIDOPHILUS AND LACTOBACILLUS PLANTARUM IN PATIENTS WITH POLYPS OR COLORECTAL CÂNCER

Arquivos De Gastroenterologia
Nazi ZinatizadehSomayeh Yaslianifard

Abstract

Colorectal cancer is one of the major causes of death worldwide. Many studies have been done on the biology of its formation as well as its treatment in recent years. One of the factors involved in the formation or treatment of this malignancy can be attributed to the microbial flora in the intestine. This study investigate the potential preventive effect of Lactobacillus acidophilus and Lactobacillus plantarum in patients with polyps or colorectal cancer (CRC). A total of 77 samples were selected in the form of three groups including individuals suffering from CRC, polyps and healthy subjects. Genomic DNA of fecal specimens and standard strains were extracted and amplified employing primers targeting of the 16S rRNA gene for initial detection. Absolute Real Time PCR quantification was used to determine the copy of the bacterial expression per gram of feces. No significant difference were observed between age and gender in the mentioned groups (P=0.06). The average copy number of Lactobacillus acidophilus shows Significant difference between the healthy group and those with polyps (P<0.0001), the healthy group and those with colorectal cancer (P<0.0001), as well as those with polyps and the colorectal cancer patients (P<0.0001)...Continue Reading

References

May 1, 1979·Cancer·R R RickertJ M Frasca
Jan 12, 2000·Archives of Environmental Contamination and Toxicology·A S PimentaA M Solanas
Jun 7, 2000·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·A KabaC Chany
Feb 7, 2001·The American Journal of Clinical Nutrition·C StantonR P Ross
Jun 11, 2002·Annual Review of Nutrition·Lora V HooperJeffrey I Gordon
Mar 12, 2008·International Journal of Colorectal Disease·Bijan Moghimi-DehkordiMohammad Reza Zali
Sep 1, 2009·The Journal of Nutritional Biochemistry·Cindy D Davis, John A Milner
Aug 12, 2014·Cancer Prevention Research·Joseph P ZackularPatrick D Schloss
Oct 14, 2014·World Journal of Gastroenterology : WJG·Francesco RussoAntonella Orlando
Aug 14, 2015·World Journal of Gastroenterology : WJG·Sai Manasa JandhyalaD Nageshwar Reddy
Dec 18, 2015·Gastrointestinal Tumors·Ya-Na Yu, Jing-Yua Fang
Aug 4, 2016·Clinical Interventions in Aging·Karen Simon
Dec 4, 2016·Digestive Diseases and Sciences·Sumedha V ChablaniSteven H Itzkowitz
Jul 6, 2017·Journal of Gastroenterology and Hepatology·Zhaohua ShenXiaoyan Wang
Dec 6, 2017·World Journal of Gastroenterology : WJG·Bożena CukrowskaUrszula Grzybowska-Chlebowczyk
Mar 8, 2018·United European Gastroenterology Journal·Jordi GordilloEugeni Domènech

❮ Previous
Next ❯

Citations

Jul 6, 2020·Toxicon : Official Journal of the International Society on Toxinology·Khawla EzdiniSamir Abbès
May 8, 2021·Frontiers in Pharmacology·Lingli RenYang Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.