Potential Repurposed Therapeutics and New Vaccines against COVID-19 and Their Clinical Status

SLAS Discovery
Abid H BandaySheikh J Ajaz

Abstract

SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was first reported in Wuhan, China, in December 2019. Since then, the virus has stretched its grip to almost all the countries in the world, affecting millions of people and causing enormous casualties. The World Health Organization (WHO) declared COVID-19 a pandemic on March 11, 2019. As of June 12, 2020, almost 7.30 million people have already been infected globally, with 413,000 reported casualties. In the United States alone, 2.06 million people have been infected and 115,000 have succumbed to this pandemic. A multipronged approach has been launched toward combating this pandemic, with the main focus on exhaustive screening, developing efficacious therapies, and vaccines for long-term immunity. Several pharmaceutical companies in collaboration with various academic institutions and governmental organizations have started investigating new therapeutics and repurposing approved drugs so as to find fast and affordable treatments against this disease. The present communication is aimed at highlighting the efforts that are currently underway to treat or prevent SARS-CoV-2 infection, with details on the science, clinical status, and timeline for selected inves...Continue Reading

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Clinical Trials Mentioned

ISRCTN83971151
NCT04292730
NCT04336904
NCT04291729
NCT04283461
NCT04336410

Software Mentioned

CanSino
Arcturus
Regeneron
Solidarity

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