Potential risk factors and incidence of pulmonary thromboembolism in Japan: results from an overview of mailed questionnaires and matched case-control study

Circulation Journal : Official Journal of the Japanese Circulation Society
Koichiro SugimuraKunio Shirato

Abstract

The potential risk factors for pulmonary thromboembolism (PTE) have not been examined in Japan, so the aims of the present study were to assess independent risk factors for PTE, and to estimate the recent incidence of symptomatic PTE. Based on a mailed questionnaire, the potential risk factors for PTE were prospectively assessed using a matched case - control study, and the number of new patients with PTE in 2004 was calculated prospectively. In multivariate analyses, increase in body mass index (odds ratio (OR) = 2.85 by 10 kg/m2; 95% confidence interval (CI), 1.51-5.39), prolonged immobilization (OR, 8.14; 95% CI, 3.15-20.99), recent major surgery (OR, 6.78; 95% CI, 2.65-17.32), and cancer (OR, 2.72; 95% CI, 1.25-5.95) were identified as independent risk factors for PTE in Japan. The risks for atherosclerosis (diabetes mellitus, hypertension, hyperlipidemia, and smoking), and alcohol consumption did not affect the incidence of PTE. The calculated number of new patients with PTE per year was 4,108 (95% CI, 3,564-4,712) in 2004. The independent risk factors for PTE in Japan are body mass index, prolonged immobilization, recent major surgery, and cancer. The number of new patients with PTE in 2004 did not demonstrate an upward t...Continue Reading

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Citations

Aug 29, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Nobuhiro TanabeTakayuki Kuriyama
Oct 30, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Masahito SakumaKunio Shirato
Nov 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Takahiro YasuiTakayuki Kuriyama
Aug 19, 2008·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sotiris PapaspyrosDavid J O'Regan
Jun 13, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Satoshi OtaMasaaki Ito
Apr 29, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Takao KobayashiTsuyomu Ikenoue
Sep 12, 2007·The Journal of Obstetrics and Gynaecology Research·Yoriko TsujiHiroshi Kobayashi
Mar 13, 2020·Neuropsychiatric Disease and Treatment·Masahiro TakeshimaKazuo Mishima
Oct 22, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Ayako ShigetaTakayuki Kuriyama
Dec 20, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Masahito SakumaTakao Kobayashi

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