Potential Risk of Hypoglycemia in Patients with Heart Failure

International Heart Journal
Yasushi TeshimaNaohiko Takahashi

Abstract

The properties of glucose changes in patients with chronic heart failure remain elusive. In the present study, we investigated the sequential changes of interstitial glucose concentrations in patients with chronic heart failure and heart disease who were not undergoing antidiabetic therapy.A glucose monitoring device (FreeStyle Libre Pro) was attached to the backside of an upper arm and the interstitial glucose concentration was monitored every 15 minutes for 1 week. Eleven patients with chronic heart failure (Heart failure (+) ) and 7 patients with chronic heart diseases but not with heart failure (Heart failure (-) ) were enrolled. The average level and peak value of interstitial glucose concentrations, and the duration of hyperglycemia (≥ 140 mg/dL) were not significantly different between Heart failure (+) and Heart failure (-). The duration of hypoglycemia (< 80 mg/dL) was significantly longer and the trough value was significantly lower in Heart failure (+) compared with Heart failure (-). Most of the patients in Heart failure (+) were exposed to a long duration of hypoglycemia from midnight to morning. Importantly, none of the patients who showed hypoglycemia complained of any subjective symptoms during hypoglycemia. Mal...Continue Reading

References

Sep 4, 1999·Journal of Internal Medicine·L Landstedt-HallinP E Lins
Dec 18, 2008·The Journal of Clinical Endocrinology and Metabolism·M Hassan MuradVictor M Montori
Oct 12, 2010·The New England Journal of Medicine·Sophia ZoungasUNKNOWN ADVANCE Collaborative Group
Jun 16, 2012·Diabetes Care·Rozalina G McCoySteven A Smith
Aug 2, 2014·Cardiovascular Research·Shotaro SaitoNaohiko Takahashi
Oct 27, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Shotaro SaitoNaohiko Takahashi
Jan 1, 2017·International Journal of Cardiology·Yuki IkedaJunya Ako
May 14, 2019·Heart Failure Clinics·Fabio MarsicoStefania Paolillo

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Citations

Jul 31, 2020·International Heart Journal·Takayuki Fujiwara, Norifumi Takeda

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