In December 2013, during a Zika virus (ZIKV) outbreak in French Polynesia, a patient in Tahiti sought treatment for hematospermia, and ZIKV was isolated from his semen. ZIKV transmission by sexual intercourse has been previously suspected. This observation supports the possibility that ZIKV could be transmitted sexually.
Disorder of spermatogenesis and viral discharge into semen in boars infected with Japanese encephalitis virus (author's transl)
Detection of dengue virus genome in urine by real-time reverse transcriptase PCR: a laboratory diagnostic method useful after disappearance of the genome in serum
Zika virus infection complicated by Guillain-Barre syndrome--case report, French Polynesia, December 2013
Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014
Rapid Spread of Zika Virus in The Americas--Implications for Public Health Preparedness for Mass Gatherings at the 2016 Brazil Olympic Games
Aedes and the triple threat of DENV, CHIKV, ZIKV--Arboviral risks and prevention at the 2016 Rio Olympic games
First Complete Genome Sequence of Zika Virus (Flaviviridae, Flavivirus) from an Autochthonous Transmission in Brazil
Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission - Continental United States, 2016
Re-Emergence of Zika Virus: A Review on Pathogenesis, Clinical Manifestations, Diagnosis, Treatment, and Prevention
Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016
Update: Interim Guidance for Health Care Providers Caring for Women of Reproductive Age with Possible Zika Virus Exposure--United States, 2016
Particulate delivery systems for vaccination against bioterrorism agents and emerging infectious pathogens
The global spread of Zika virus: is public and media concern justified in regions currently unaffected?
Zika virus infection during pregnancy and microcephaly occurrence: a review of literature and Brazilian data
Comparison of Test Results for Zika Virus RNA in Urine, Serum, and Saliva Specimens from Persons with Travel-Associated Zika Virus Disease - Florida, 2016
Rift Valley fever in kidney transplant recipient returning from Mali with viral RNA detected in semen up to four months from symptom onset, France, autumn 2015
An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors
Review: A neglected Flavivirus: an update on Zika virus in 2016 and the future direction of research
Utilizing Nontraditional Data Sources for Near Real-Time Estimation of Transmission Dynamics During the 2015-2016 Colombian Zika Virus Disease Outbreak
Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in the United States, 1995-2016 (Diptera: Culicidae)
Prevention and Control of Zika as a Mosquito-Borne and Sexually Transmitted Disease: A Mathematical Modeling Analysis
Viral load kinetics of Zika virus in plasma, urine and saliva in a couple returning from Martinique, French West Indies
Outbreak of Zika virus disease in the Americas and the association with microcephaly, congenital malformations and Guillain-Barré syndrome
The Emergence of Zika Virus as a Global Health Security Threat: A Review and a Consensus Statement of the INDUSEM Joint working Group (JWG)
The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact
Detection of Zika virus RNA in whole blood of imported Zika virus disease cases up to 2 months after symptom onset, Israel, December 2015 to April 2016
Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59
Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016
Travel-associated and autochthonous Zika virus infection in mainland France, 1 January to 15 July 2016
Infection dynamics in a traveller with persistent shedding of Zika virus RNA in semen for six months after returning from Haiti to Italy, January 2016
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs
De Novo Structural Modeling and Conserved Epitopes Prediction of Zika Virus Envelop Protein for Vaccine Development
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
New Paradigms for Virus Detection, Surveillance and Control of Zika Virus Vectors in the Settings of Southeast Asia
Update: Interim Guidance for Preconception Counseling and Prevention of Sexual Transmission of Zika Virus for Persons with Possible Zika Virus Exposure - United States, September 2016
Zika virus - emergence, evolution, pathology, diagnosis, and control: current global scenario and future perspectives - a comprehensive review
Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Zika Virus Outbreak in Rio de Janeiro, Brazil: Clinical Characterization, Epidemiological and Virological Aspects
Transmission Dynamics of Zika Virus in Island Populations: A Modelling Analysis of the 2013-14 French Polynesia Outbreak
The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model
Relative analytical sensitivity of donor nucleic acid amplification technology screening and diagnostic real-time polymerase chain reaction assays for detection of Zika virus RNA
Fast preparation of a long chimeric armored RNA as controls for external quality assessment for molecular detection of Zika virus
Zika in Rio de Janeiro: Assessment of basic reproduction number and comparison with dengue outbreaks
ZikaVR: An Integrated Zika Virus Resource for Genomics, Proteomics, Phylogenetic and Therapeutic Analysis
Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells
Vector status of Aedes species determines geographical risk of autochthonous Zika virus establishment
Determination of the Cell Permissiveness Spectrum, Mode of RNA Replication, and RNA-Protein Interaction of Zika Virus
Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: A systematic review
Mosquito Control Practices and Zika Knowledge Among Outdoor Construction Workers in Miami-Dade County, Florida
DETECTION OF HUMAN ANTI-ZIKA VIRUS IgG BY ELISA USING AN ANTIGEN FROM in vitro INFECTED VERO CELLS: PRELIMINARY RESULTS
Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?
Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus
Molecular detection of Zika virus in blood and RNA load determination during the French Polynesian outbreak
High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus
Sulfated Glycans and Related Digestive Enzymes in the Zika Virus Infectivity: Potential Mechanisms of Virus-Host Interaction and Perspectives in Drug Discovery
Skin manifestations are common and associated with a higher prevalence of congenital abnormalities in Zika virus infection
Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques
Zika virus RNA polymerase chain reaction on the utility channel of a commercial nucleic acid testing system
Recombinant Zika virus envelope protein elicited protective immunity against Zika virus in immunocompetent mice
Unintended consequences and the paradox of control: Management of emerging pathogens with age-specific virulence
Differences Between Florida and the Rest of the United States in Response to Local Transmission of the Zika Virus: Implications for Future Communication Campaigns
First insights into insecticidal activity against Aedes aegypti and partial biochemical characterization of a novel low molecular mass chymotrypsin-trypsin inhibitor purified from Lonchocarpus sericeus seeds
Prevention and Control Strategies to Counter Zika Virus, a Special Focus on Intervention Approaches against Vector Mosquitoes-Current Updates
ZIKV infection effects changes in gene splicing, isoform composition and lncRNA expression in human neural progenitor cells
Cutting Edge: Innate Immune Augmenting Vesicular Stomatitis Virus Expressing Zika Virus Proteins Confers Protective Immunity
Evaluation of a field-deployable reverse transcription-insulated isothermal PCR for rapid and sensitive on-site detection of Zika virus
CD14+ CD16+ monocytes are the main target of Zika virus infection in peripheral blood mononuclear cells in a paediatric study in Nicaragua
Patchy DNA forms of the Zika virus RNA genome are generated following infection in mosquito cell cultures and in mosquitoes
Surveillance of microcephaly and selected brain anomalies in Argentina: Relationship with Zika virus and other congenital infections
Dengue immune sera enhance Zika virus infection in human peripheral blood monocytes through Fc gamma receptors
Ghost probiotics with a combined regimen: a novel therapeutic approach against the Zika virus, an emerging world threat
Estimating the effects of variation in viremia on mosquito susceptibility, infectiousness, and R0 of Zika in Aedes aegypti
Production and characterization of Zika virus RNA reference reagents as a response to a public health emergency
Variations in maternal adenylate cyclase genes are associated with congenital Zika syndrome in a cohort from Northeast, Brazil
Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone
Equine Arteritis Virus Has Specific Tropism for Stromal Cells and CD8(+) T and CD21(+) B Lymphocytes but Not for Glandular Epithelium at the Primary Site of Persistent Infection in the Stallion Reproductive Tract
Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model
Zika Virus Testing Considerations: Lessons Learned from the First 80 Real-Time Reverse Transcription-PCR-Positive Cases Diagnosed in New York State
A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development
Social determinants of health associated with topical repellent use in pregnancy: a cross-sectional study during a Zika outbreak in Brazil
Epidemiologic investigation of a family cluster of imported ZIKV cases in Guangdong, China: probable human-to-human transmission
Study on the persistence of Zika virus (ZIKV) in body fluids of patients with ZIKV infection in Brazil
Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals
Australia’s notifiable disease status, 2015: Annual report of the National Notifiable Diseases Surveillance System
Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection.
Development of a fluorescence-based method for the rapid determination of Zika virus polymerase activity and the screening of antiviral drugs
Guillain-Barre syndrome and Zika infection: identifying leading producers, countries relative specialization and collaboration
Knowledge and perceptions of Zika virus transmission in the community of Puerto Plata, Dominican Republic
Environmental and social determinants of population vulnerability to Zika virus emergence at the local scale
A chip-based potentiometric sensor for a Zika virus diagnostic using 3D surface molecular imprinting
Zika Virus Causes Acute Infection and Inflammation in the Ovary of Mice Without Apparent Defects in Fertility
Contribution of intertwined loop to membrane association revealed by Zika virus full-length NS1 structure
Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model
Identification of anti-flaviviral drugs with mosquitocidal and anti-Zika virus activity in Aedes aegypti
Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies
Community context and sub-neighborhood scale detail to explain dengue, chikungunya and Zika patterns in Cali, Colombia
Transmission Dynamics and Control Mechanisms of Vector-Borne Diseases with Active and Passive Movements Between Urban and Satellite Cities
Development of Universal and Lineage-Specific Primer Sets for Rapid Detection of the Zika Virus (ZIKV) in Blood and Urine Samples Using One-Step Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP)
Zika virus proteins at an atomic scale: how does structural biology help us to understand and develop vaccines and drugs against Zika virus infection?
Development of a Flow-Free Automated Colorimetric Detection Assay Integrated with Smartphone for Zika NS1
New estimates of the Zika virus epidemic attack rate in Northeastern Brazil from 2015 to 2016: A modelling analysis based on Guillain-Barré Syndrome (GBS) surveillance data
Oral and maxillofacial outcomes in children with microcephaly associated with the congenital Zika syndrome
Performance of an Automated Zika IgG Immunoassay in the Detection of Zika IgG Specific Antibodies-A Validation Approach in Samples from Prevalence Areas and Non-Endemic Countries
Modeling mosquito-borne and sexual transmission of Zika virus in an enzootic host, the African green monkey
Zika virus tropism during early infection of the testicular interstitium and its role in viral pathogenesis in the testes.
Zika virus in rhesus macaque semen and reproductive tract tissues: a pilot study of acute infection†.
Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication
Epidemiology, Prevention, and Potential Future Treatments of Sexually Transmitted Zika Virus Infection
Development of a reverse transcription quantitative polymerase chain reaction-based assay for broad coverage detection of African and Asian Zika virus lineages.
Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light
Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission
Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection
Effective control of early Zika virus replication by Dengue immunity is associated to the length of time between the 2 infections but not mediated by antibodies
Molecular Basis of Differential Stability and Temperature Sensitivity of ZIKA versus Dengue Virus Protein Shells
DZC DIAG: mobile application based on expert system to aid in the diagnosis of dengue, Zika, and chikungunya
Harmonization of nucleic acid testing for Zika virus: development of the 1st World Health Organization International Standard
Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone
Zika Virus Infects Trabecular Meshwork and Causes Trabeculitis and Glaucomatous Pathology in Mouse Eyes
Community participation in mosquito breeding site control: an interdisciplinary mixed methods study in Curaçao
Risk of Contamination of Gametes and Embryos during Cryopreservation and Measures to Prevent Cross-Contamination
Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages
Mathematical Analysis of Viral Replication Dynamics and Antiviral Treatment Strategies: From Basic Models to Age-Based Multi-Scale Modeling
Complete Genome Sequences of Zika Virus Strains Used for the Formulation of CBER/FDA RNA Reference Reagents and Lot Release Panels for Nucleic Acid Technology Testing
Rapid diagnosis of Zika virus through saliva and urine by Loop-mediated isothermal amplification (LAMP)
Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals
Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region
Prevalence of Zika and malaria in patients with fever in secondary healthcare facilities in south-eastern Nigeria
Harmonization of Zika neutralization assays by using the WHO International Standard for anti-Zika virus antibody
Mosquito Control Activities during Local Transmission of Zika Virus, Miami-Dade County, Florida, USA, 2016
Vector competence of Culex mosquitoes (Diptera: Culicidae) in Zika virus transmission: an integrative review
MATERNAL ZIKA VIRUS (ZIKV) INFECTION FOLLOWING VAGINAL INOCULATION WITH ZIKV-INFECTED SEMEN IN THE TIMED-PREGNANT OLIVE BABOON
Analysis of Ribonucleotide 5'-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays
Evolution of Two Major Zika Virus Lineages: Implications for Pathology, Immune Response, and Vaccine Development
Performance of the Trioplex real-time RT-PCR assay for detection of Zika, dengue, and chikungunya viruses
Phylogenetic surveillance of travel-related Zika virus infections through whole-genome sequencing methods
The E3 ligase TRIM56 is a host restriction factor of Zika virus and depends on its RNA-binding activity but not miRNA regulation, for antiviral function
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization
Update: Interim Guidance for Preconception Counseling and Prevention of Sexual Transmission of Zika Virus for Men with Possible Zika Virus Exposure - United States, August 2018
Development of a Rapid Diagnostic Test Kit to Detect IgG/IgM Antibody against Zika Virus Using Monoclonal Antibodies to the Envelope and Non-structural Protein 1 of the Virus
Modeling Zika Virus Transmission Dynamics: Parameter Estimates, Disease Characteristics, and Prevention
Knowledge regarding Zika Virus Infection among Healthcare Providers in an Academic Tertiary Care Center in Riyadh, Saudi Arabia: A Cross-Sectional Survey Study
Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869
Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus.
Mechanistic Target of Rapamycin Signaling Activation Antagonizes Autophagy To Facilitate Zika Virus Replication
Evidence That Zika Virus Is Transmitted by Breastfeeding to Newborn A129 (Ifnar1 Knock-Out) Mice and Is Able to Infect and Cross a Tight Monolayer of Human Intestinal Epithelial Cells
Pregnancy Alters Innate and Adaptive Immune Responses to Zika Virus Infection in the Reproductive Tract.
Amyloid precursor protein is a restriction factor that protects against Zika virus infection in mammalian brains.
A reverse transcription loop-mediated isothermal amplification for broad coverage detection of Asian and African Zika virus lineages
A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy
Two immunogenic recombinant protein vaccine candidates showed disparate protective efficacy against Zika virus infection in rhesus macaques.
Uncertainty in times of medical emergency: Knowledge gaps and structural ignorance during the Brazilian Zika crisis
Endocrine Dysfunction in Children with Zika-Related Microcephaly Who Were Born during the 2015 Epidemic in the State of Pernambuco, Brazil.
Development and validation of a one-step reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid detection of ZIKV in patient samples from Brazil.
Immunoinformatics guided rational design of a next generation multi epitope based peptide (MEBP) vaccine by exploring Zika virus proteome
Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro.
Zika virus disrupts the barrier structure and Absorption/Secretion functions of the epididymis in mice.
Amyloid precursor protein is a restriction factor that protects against Zika virus infection in mammalian brains
Duration of seminal Zika viral RNA shedding in immunocompetent mice inoculated with Asian and African genotype viruses.
Recovery of Synthetic Zika Virus Based on Rio-U1 Isolate Using a Genetically Stable Two Plasmid System and cDNA Amplification.
Estimate of the reproduction number of the 2015 Zika virus outbreak in Barranquilla, Colombia, and estimation of the relative role of sexual transmission
Zika E Glycan Loop Region and Guillain-Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to Be Taken in Account for Vaccine Development.
Sofosbuvir Selects for Drug-Resistant Amino Acid Variants in the Zika Virus RNA-Dependent RNA-Polymerase Complex In Vitro.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Alzheimer's Disease: MS4A
Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.
Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.
Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.
Genetic Screens in iPSC-derived Brain Cells
Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.
This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Pharmacology of Proteinopathies
This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.
Alignment-free Sequence Analysis Tools
Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.