Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence

Journal of Tropical Medicine
Sashini D PereraChanika D Jayasinghe

Abstract

Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue. Though, E. hirta has been extensively investigated for numerous bioactivities, limited studies have been conducted on the antidengue activity. Thus, the present study provides a comprehensive review of studies conducted on the antidengue activity of E. hirta. A systematic literature survey was carried out in scientific databases, PubMed®, Scopus, and Google Scholar, for research carried on the antidengue activity of E. hirta. The literature search identified a total of 867 articles: databases PubMed = 6, Scopus SciVerse® = 423, and Google Scholar = 437; one additional article was identified by searching reference lists. Eight full papers were entitled to the review; out of those, two studies focused on ethnobotanical surveys, three on animal experiments, one on human trial, and two on in vitro antiviral activities, and one was computational study. The available evidence conclusively demonstrates the potential of E. hirta against dengue as it holds significant antiviral and platelet increasing activities. However, the number of studies conducted to validate its antidengue activity was found to be inade...Continue Reading

References

Jul 17, 1998·Clinical Microbiology Reviews·D J Gubler
Mar 4, 2005·Emerging Themes in Epidemiology·Debarati Guha-Sapir, Barbara Schimmer
Oct 14, 2009·Clinical Microbiology Reviews·Byron E E MartinaAlbert D M E Osterhaus
Oct 20, 2011·The New England Journal of Medicine·UNKNOWN RTS,S Clinical Trials PartnershipPreeti Vansadia
Dec 12, 2012·Pharmacognosy Research·Priyanga RanasingheSaman B Gunatilake
Feb 26, 2013·PLoS Neglected Tropical Diseases·Donald S ShepardYara A Halasa
Apr 18, 2013·Journal of Natural Medicines·Siti Latifah Abd KadirRazauden Mohamed Zulkifli
May 11, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Soobitha SubenthiranZakiah Ismail
Jan 5, 2014·BioMed Research International·Kwan Yuet PingSreenivasan Sasidharan
Feb 15, 2016·The Lancet Infectious Diseases·Jeffrey D StanawayChristopher J L Murray
Jul 2, 2016·Journal of Intercultural Ethnopharmacology·Gerard Quinto de GuzmanGrecebio Jonathan Duran Alejandro
Apr 28, 2017·BMC Complementary and Alternative Medicine·Chanika Dilumi JayasinghePreethi Vidya Udagama

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Citations

Apr 7, 2020·Journal of Biomolecular Structure & Dynamics·Vasudevan SaranyaSubramaniam Vijayakumar
Nov 30, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Chanika D Jayasinghe, Uthpala A Jayawardena
Oct 30, 2020·Phytotherapy Research : PTR·Faraat AliAsad Ali
Dec 23, 2020·Pharmaceutical Patent Analyst·Sukhbir K Shahid

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