Potential vascular and bleeding complications of treatment with selective serotonin reuptake inhibitors

Psychosomatics
B P Skop, T M Brown

Abstract

Selective serotonin reuptake inhibitors (SSRIs) alter peripheral handling of serotonin, leading to potential side effects. Further, the majority of the body's serotonin is found outside the central nervous system. Peripheral serotonin is important in platelet aggregation and the modulation of vascular tone. SSRIs block platelet uptake and pulmonary endothelial metabolism of serotonin, and use of these agents may conceivably result in bleeding and vasospastic complications.

References

Jan 1, 1990·Journal of Cardiovascular Pharmacology·G M Tyce
Dec 1, 1992·The American Journal of Psychiatry·D W Gunzberger, D Martinez
Mar 1, 1992·The American Journal of Psychiatry·J Aranth, C Lindberg
Dec 1, 1991·International Clinical Psychopharmacology·S J Warrington
Jan 1, 1990·Progress in Neuro-psychopharmacology & Biological Psychiatry·S P TyrerH W Griffiths
Feb 1, 1991·Annals of Emergency Medicine·S F GardnerE A Panacek
Nov 1, 1994·The American Journal of Emergency Medicine·B P SkopT M Brown
May 1, 1994·The American Journal of Psychiatry·J P OttervangerJ N Weeda
May 1, 1993·Psychological Medicine·S M Stahl
Feb 1, 1993·Journal of Clinical Psychopharmacology·T HoeksemaG M Van Kempen

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Citations

Feb 1, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Amirali SayadipourD Greg Anderson
Jul 20, 2010·Wiener medizinische Wochenschrift·Markus GoschUlrike Sommeregger
Jul 18, 2009·Journal of Inherited Metabolic Disease·M WalterfangD Velakoulis
Jun 12, 2008·International Ophthalmology·Alastair D HardistySay Aun Quah
May 25, 2007·Current Psychiatry Reports·Brian Keefe
Jun 15, 1997·Biological Psychiatry·A RudnickA Zelikovski
Jan 11, 2001·Physiology & Behavior·P F Frohlich, C M Meston
Nov 1, 2000·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·F J de AbajoD Montero
May 25, 2002·Journal of the American Geriatrics Society·Michael Smith, Dave Robinson
Apr 6, 2011·Cardiology in Review·Christopher M Celano, Jeff C Huffman
Jul 12, 2011·Therapeutic Drug Monitoring·Kelly A CochranJeffrey R Bishop
Apr 7, 2007·International Clinical Psychopharmacology·Yan ChenSiyan Zhan
Sep 20, 2005·The Australian and New Zealand Journal of Psychiatry·Mark WalterfangChristos Pantelis
Sep 10, 2005·BMJ : British Medical Journal·Carol Paton, I Nicol Ferrier
Aug 4, 2011·BMJ : British Medical Journal·Carol CouplandJulia Hippisley-Cox
Nov 5, 2003·Psychosomatics·Jennifer M Loftis, Peter Hauser
Dec 1, 2006·Neuropsychiatric Disease and Treatment·Mark WalterfangDennis Velakoulis
Jan 20, 2004·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Raymond G Schlienger, Christoph R Meier
May 14, 2008·Southern Medical Journal·Kapil ParakhRoy C Ziegelstein
Jun 14, 2000·Psychosomatic Medicine·A Camacho, J E Dimsdale
Sep 17, 2014·Journal of Clinical Psychopharmacology·Ilyas KayaMurat Coskun
Oct 11, 2001·Journal of Clinical Psychopharmacology·R I Shader, D J Greenblatt
Apr 25, 2006·Journal of Clinical Psychopharmacology·Dan AtarVictor Serebruany
Mar 18, 2008·Journal of Clinical Psychopharmacology·Erin SalkeldDavid N Juurlink
May 18, 2010·Journal of Clinical Psychopharmacology·Gianluca TrifiròMiriam C J M Sturkenboom
Mar 30, 2005·Expert Opinion on Drug Safety·Robert M WeinriebJames D Lewis
Mar 5, 2016·International Journal of Preventive Medicine·Seyed Kazem Razavi RatkiAtefeh Shirinzade
Nov 20, 2012·Psychosomatics·Hamid R TavakoliMarie A Dillard
Nov 8, 2015·European Journal of Clinical Pharmacology·Raymond NoordamLoes E Visser
Apr 20, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Sabine GruberChristoph Papp
Sep 1, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael DallJesper Hallas
Jul 2, 2009·Psychosomatics·Frank AndersohnEdeltraut Garbe
Oct 22, 2008·Critical Care Clinics·Felicia A SmithTheodore A Stern
Oct 17, 2007·The Psychiatric Clinics of North America·Madeleine BeckerElisabeth J Shakin Kunkel
Apr 14, 2006·Basic & Clinical Pharmacology & Toxicology·Francisco J de AbajoMariano Madurga
Mar 23, 2012·British Journal of Clinical Pharmacology·Mary A De Vera, Anick Bérard
Mar 8, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·A MehrabadiK S Joseph

❮ Previous
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