Potentially high-risk cardiac arrhythmias with focal to bilateral tonic-clonic seizures and generalized tonic-clonic seizures are associated with the duration of periictal hypoxemia

Epilepsia
Katherine J ParkMasud Seyal

Abstract

To investigate potentially high-risk cardiac arrhythmias (PHAs) following focal to bilateral tonic-clonic seizures (FBTCSs) and generalized tonic-clonic seizures (GTCSs) and to study the association of PHAs with seizure characteristics and the severity of associated ictal respiratory dysfunction. Electrocardiographic (EKG) and pulse oximetry (SpO2 ) data were recorded concurrently with video-electroencephalographic telemetry in the epilepsy monitoring unit (EMU). One minute of preictal EKG, the ictal EKG, and 2 min of ictal/postictal data were reviewed for each seizure. Nonsustained ventricular tachycardia, bradyarrhythmia, and/or sinus pauses were considered as PHAs. FBTCSs/GTCSs with PHAs were compared to those that had only ictal sinus tachycardia. Data from 69 patients with 182 FBTCSs/GTCSs with usable SpO2 and EKG recordings were available. There were 10 FBTCSs/GTCSs in 10 patients with a PHA. The presence of PHAs was not associated with seizure duration or SpO2 nadir. FBTCSs/GTCSs with a PHA were significantly associated with the duration of oxygen desaturation < 90% when compared with FBTCSs/GTCSs with only sinus tachycardia (Mann-Whitney, p = 0.042). Desaturation duration of <100 s was not significantly associated with ...Continue Reading

References

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Citations

Jan 16, 2019·Epilepsia·Robert D NassRainer Surges
Jan 30, 2019·Current Opinion in Neurology·Philippe RyvlinSamden D Lhatoo
Dec 21, 2018·Neurology·Sylvain RheimsUNKNOWN REPO2MSE study group
May 13, 2020·Epilepsia·Julia C M PottkämperMichel J A M van Putten
Nov 26, 2019·Clinical Practice and Cases in Emergency Medicine·Hani I KuttabDavid G Beiser
Nov 21, 2018·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Niravkumar Barot, Maromi Nei
Feb 26, 2019·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Christoph BaumgartnerSusanne Pirker
Dec 24, 2019·Experimental Neurology·Alexandra N PetrucciGordon F Buchanan
May 15, 2021·Frontiers in Veterinary Science·Enrice HuenerfauthAndrea Tipold
Jul 9, 2021·Epilepsia·Richard L VerrierSteven C Schachter
Oct 16, 2021·Neurology·Roland D Thijs, Josemir W Sander
Oct 16, 2021·Neurology·Shobi SivathambooUNKNOWN MS-BioS Study Group

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