Potentially Inappropriate Medication Use in Older Adults with Alzheimer's Disease and Related Dementias Living in the Community: A Cross-Sectional Analysis.

Drugs -- Real World Outcomes
Lauren E VickersDaniela C Moga

Abstract

With the older adult population in the USA increasing, so is the population of those with Alzheimer's disease and related dementias (ADRD). Older adults are vulnerable to the effects of potentially inappropriate medications as established by the Beers Criteria; however, some medications continue to be prescribed against recommendations. Our objectives were to describe potentially inappropriate medication (PIM) use linked to cognitive impairment or decline (referred to as Cog-PIM) in older adults with and without ADRD and to investigate whether the odds of Cog-PIM report differ by ADRD status in ambulatory care (i.e., outpatient care) in the USA. A cross-sectional analysis was performed using a nationally representative sample of non-perioperative, office-based ambulatory care visits by adults aged ≥ 65 years in 2016 (n = 218,182,131). Data were collected from the National Ambulatory Medical Care Survey. Cog-PIMs were identified as defined in the 2015 Beers Criteria recommendations for medications that may be potentially inappropriate in older adults with cognitive impairment or dementia. ADRD status was determined by clinician report using free text, the ADRD flag, or the presence of a diagnosis code indicating dementia. Multiv...Continue Reading

References

Nov 23, 2000·Journal of the Royal Society of Medicine·J Mintzer, A Burns
Sep 12, 2003·Journal of Geriatric Psychiatry and Neurology·Jerome A YesavageBarry Lebowitz
Dec 18, 2003·British Journal of Clinical Pharmacology·A A Mangoni, S H D Jackson
Jun 2, 2009·Journal of the American Geriatrics Society·Harrison G BloomPhyllis C Zee
Jun 12, 2009·Drug Metabolism Reviews·Ulrich Klotz
Apr 29, 2010·Current Psychiatry Reports·Chloe LeonDavid C Mamo
Nov 22, 2012·JAMA : the Journal of the American Medical Association·Laura N GitlinConstantine G Lyketsos
Aug 26, 2014·Journal of Alzheimer's Disease : JAD·Tilly EichlerWolfgang Hoffmann
Oct 9, 2015·Journal of the American Geriatrics Society·UNKNOWN By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel
Oct 27, 2015·Journal of the American Pharmacists Association : JAPhA·Nandita KachruRajender R Aparasu
Dec 31, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Richard A GoodmanBruce S Finke
Jun 15, 2016·Journal of the American Medical Directors Association·Mia YangJulie P W Bynum
Nov 7, 2016·Mayo Clinic Proceedings·Matej MarkotaMaria I Lapid
May 17, 2017·Canadian Pharmacists Journal : CPJ = Revue Des Pharmaciens Du Canada : RPC·Tejal PatelLinda Lee
Sep 5, 2017·Journal of Alzheimer's Disease : JAD·Amanda J CrossRohan A Elliott
Mar 27, 2018·Journal of Alzheimer's Disease : JAD·Rachel Underlien KristensenGunhild Waldemar
Mar 28, 2018·Journal of the American Geriatrics Society·Taeho Greg RheeJoseph S Ross
Aug 16, 2018·Journal of the American Medical Directors Association·Hannah DillsQuratulain Syed
Oct 10, 2018·Journal of the American Geriatrics Society·Catherine A AmmermanTara N Downs
Jan 6, 2019·European Journal of Clinical Pharmacology·Deborah HukinsJason W Boland
Jun 8, 2019·International Journal of Geriatric Psychiatry·Tesfahun C EshetieLisa M Kalisch Ellett

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