Potentially Malignant Oral Disorders and Cancer Transformation

Anticancer Research
Divya GaneshBengt Hasséus

Abstract

Cancer in the oral cavity is often preceded by precursor lesions. Nine oral mucosal disorders are known to have an increased risk of malignant transformation. The etiology varies from disorders caused by exogenous factors such as tobacco and autoimmune inflammation to idiopathic or inherited genetic aberrations. In this review, these potentially malignant disorders (PMDs) are described regarding clinical presentation and histopathological architecture. Special attention is paid to the underlying etiologies of PMDs and the potential pathways leading to cancer. The clinical perspective focuses on the importance of accurate and timely diagnosis.

Citations

May 3, 2019·International Journal of STD & AIDS·Gabriela Anaya-SaavedraMarcela Saeb-Lima
May 28, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Stefano BasilePierluigi Benedetti Panici
Jul 11, 2020·International Journal of Environmental Research and Public Health·Riccardo NociniFrancesca Zotti
Jan 26, 2021·Molecular Biology Reports·Mohd MugheesSaima Wajid
Dec 15, 2020·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·María Fernanda GalíndezMabel Brunotto
Mar 9, 2021·Expert Review of Molecular Diagnostics·Kenneth P H PritzkerDavid Mock
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Aug 28, 2021·International Journal of Environmental Research and Public Health·Shih-Wei YangCheng-Cheng Hwang

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