Potentially pathogenic microorganisms in the oral cavity during febrile episodes in immunocompromised patients with haematologic malignancies

Scandinavian Journal of Infectious Diseases
O J BergmannJ Ellegaard

Abstract

The purpose of the study was to describe the occurrence of potentially pathogenic microorganisms during febrile episodes in haematologic patients, who had been treated with anti-neoplastic drugs within the previous 4 weeks. During a 9-month period 78 consecutive febrile episodes occurred in 46 patients who were examined daily. On day 1, before antibiotic treatment was started, members of the normal flora were found in 83%, Candida spp. in 72%, Enterobacteriaceae in 29%, Pseudomonas aeruginosa in 8%, Staphylococcus aureus in 14%, coagulase-negative staphylococci in 26% and enterococci in 17% of the febrile episodes. During the subsequent antibiotic treatment, the prevalence of members of the normal oral flora was markedly reduced from day 1 (83%) to day 7 (6%), and the normal flora was replaced by potentially pathogenic microorganisms. A rise was found in the prevalences of Candida spp. (from 72 to 92%) and coagulase-negative staphylococci (from 26 to 49%) from day 1 to day 4. The prevalences of Enterobacteriaceae and P. aeruginosa showed no day-to-day changes, and were not different in patients hospitalized for more or less than 24 h prior to inclusion into the study, suggesting that their detection was not due to acquisition d...Continue Reading

References

Jun 1, 1976·Journal of Periodontal Research·C R SchiottH Löe
May 1, 1979·The American Journal of the Medical Sciences·J L LeFrockL Weinstein
Jan 1, 1968·Acta Pathologica Et Microbiologica Scandinavica·B GästrinA Marcetic
Nov 20, 1969·The New England Journal of Medicine·W G JohansonJ P Sanford
Aug 1, 1984·Journal of Oral Pathology·L P SamaranayakeJ Willox
Jul 1, 1981·The Journal of Infectious Diseases·V FainsteinG P Bodey
Oct 1, 1982·The Journal of Infectious Diseases·G PetersG Pulverer

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Citations

Mar 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·O J BergmannJ Ellegaard
Sep 1, 1996·European Journal of Cancer. Part B, Oral Oncology·J L SixouM Bonnaure-Mallet
Mar 24, 1998·Oral Oncology·J H MeurmanC Lindqvist
Jan 12, 2001·Oral Microbiology and Immunology·E C SheehyG J Roberts
Jul 1, 1991·Journal of Clinical Periodontology·J Slots, T E Rams
Sep 1, 1991·Oral Surgery, Oral Medicine, and Oral Pathology·Y B WahlinM Sjöström
Feb 7, 2001·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·R Häyrinen-ImmonenC Lindqvist
Jan 1, 1990·Scandinavian Journal of Infectious Diseases·O J Bergmann, P L Andersen
Jun 22, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Judith A E M ZechaLudi E Smeele
Jul 31, 1998·FEMS Immunology and Medical Microbiology·E Majda-Stanislawska, Z Krzeminski
Aug 1, 1996·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·L Bunetel, M Bonnaure-Mallet
Mar 24, 2018·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Kelly Rocio Vargas VillafuerteDaniela Bazan Palioto

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