PMID: 2097101Jan 1, 1990Paper

Potentiated depression of indirectly evoked twitch tension of rat soleus muscle following arterial blood occlusion in the presence of ketamine

The Chinese Journal of Physiology
K K Wong

Abstract

The presence of ketamine, in a dose insufficient to depress the indirectly evoked twitch tension of soleus muscle, was shown to significantly potentiate the depression of the indirectly evoked twitch tension following a 10-min occlusion of the arterial blood to this muscle. Since ketamine was known to be an uncoupling agent in oxidative phosphorylation, it was possible that its uncoupling property potentiated the effect of the 10-min blood occlusion to depress the indirectly evoked twitch tension of soleus muscle.

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