Poultry-associated Salmonella enterica subsp. enterica serovar 4,12:d:- reveals high clonality and a distinct pathogenicity gene repertoire.

Applied and Environmental Microbiology
Stephan HuehnBurkhard Malorny

Abstract

A European baseline survey during the years 2005 and 2006 has revealed that the monophasic Salmonella enterica subsp. enterica serovar 4,12:d:- was, with a prevalence of 23.6%, the most frequently isolated serovar in German broiler flocks. In Denmark and the United Kingdom, its serovar prevalences were 15.15% and 2.8%, respectively. Although poultry is a major source of human salmonellosis, serovar 4,12:d:- is rarely isolated in humans (approximately 0.09% per year). Molecular typing studies using pulsed-field gel electrophoresis and DNA microarray analysis show that the serovar is highly clonal and lacks genes with known contributions to pathogenicity. In contrast to other poultry-associated serovars, all strains were susceptible to 17 antimicrobial agents tested and did not encode any resistance determinant. Furthermore, serovar 4,12:d:- lacked the genes involved in galactonate metabolism and in the glycolysis and glyconeogenesis important for energy production in the cells. The conclusion of the study is that serovar 4,12:d:- seems to be primarily adapted to broilers and therefore causes only rare infections in humans.

References

Jan 9, 1996·Proceedings of the National Academy of Sciences of the United States of America·A J BäumlerF Heffron
Feb 24, 2001·Revue Scientifique Et Technique·C J Thorns
Jun 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E J Baron
Jul 4, 2001·Veterinary Research·S Schwarz, E Chaslus-Dancla
May 31, 2003·Journal of Bacteriology·P AmavisitP F Markham
Aug 20, 2004·Journal of Bacteriology·S PorwollikM McClelland
Dec 3, 2004·Applied and Environmental Microbiology·Burkhard MalornyReiner Helmuth
Apr 13, 2005·Journal of Microbiological Methods·Angela H A M van HoekHenk J M Aarts
Jun 7, 2005·Journal of Microbiological Methods·Alessandra CarattoliE John Threlfall
Apr 11, 2006·Foodborne Pathogens and Disease·P Gerner-SmidtUNKNOWN Pulsenet Taskforce
Jun 9, 2006·Microbiology and Molecular Biology Reviews : MMBR·Mark A TolemanTimothy R Walsh
Oct 13, 2006·Molecular and Cellular Probes·Burkhard MalornyReiner Helmuth
Jun 9, 2007·Journal of Microbiological Methods·Catherine YoshidaKris Rahn
Sep 28, 2007·The Journal of Antimicrobial Chemotherapy·T MajtanV Majtan
Apr 1, 2008·Trends in Microbiology·John R McQuistonJohn M Logsdon
May 9, 2008·The Journal of Infectious Diseases·Timothy F JonesFrederick J Angulo

❮ Previous
Next ❯

Citations

Mar 10, 2012·Foodborne Pathogens and Disease·Elisabeth HauserBurkhard Malorny
Jun 28, 2011·Applied and Environmental Microbiology·Janine BeutlichUNKNOWN Med-Vet-Net WP21 Project Group
May 12, 2009·Applied and Environmental Microbiology·T W Raymond ChiaGary A Dykes
Jun 25, 2013·Applied and Environmental Microbiology·Anne ToboldtBurkhard Malorny
May 18, 2010·Applied and Environmental Microbiology·Elisabeth HauserBurkhard Malorny
Sep 16, 2011·International Journal of Food Microbiology·Elisabeth HauserBurkhard Malorny
Nov 26, 2010·International Journal of Food Microbiology·Henk J M AartsBurkhard Malorny
Sep 8, 2010·International Journal of Food Microbiology·Hugo GrønlundJeffrey Hoorfar
Jul 27, 2010·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Eva LitrupEva M Nielsen
May 12, 2007·Acta Veterinaria Scandinavica·Nanna Lindqvist, Sinikka Pelkonen
May 22, 2016·Infectious Disease Clinics of North America·Andrea Endimiani, Michael R Jacobs
Apr 11, 2015·PloS One·Cary Pirone-DaviesMarc W Allard
Apr 1, 2015·International Journal of Environmental Research and Public Health·Denise Myriam DekkerJürgen May
Sep 25, 2021·International Microbiology : the Official Journal of the Spanish Society for Microbiology·Sahin Namli, Yesim Soyer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.