PMID: 9523810Apr 2, 1998Paper

Povidone iodine and skin disinfection before initiation of epidural anesthesia

Anesthesiology
David J BirnbachEmilia M Sordillo

Abstract

Povidone iodine (PI) solution is used commonly for skin disinfection before epidural and spinal anesthesia. Although there have been reports indicating the presence of microbial contaminants in PI solution, none have evaluated the prevalence of PI contamination. The aims of this study were to assess the frequency of bacterial contamination of previously opened bottles of PI solution and to compare the effectiveness of new and previously opened bottles of PI solution for skin disinfection. Twenty previously opened and ten previously unopened multiple-use bottles of PI solution were evaluated for microbial contamination. In addition, final swabs and PI solution used for skin disinfection in 80 patients undergoing elective epidural analgesia were evaluated. The inside of the bottle cap or the PI solution from 40% of the multiple-use PI bottles in use were contaminated. There was no growth from any previously unused PI bottles. Povidone iodine from newly opened bottles provided more effective skin decontamination than did solution from previously opened bottles. Multiple-use PI bottles in normal use may become contaminated by bacteria. In addition, PI solution from previously opened bottles was less effective than PI from previousl...Continue Reading

References

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Citations

Mar 7, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Ismail Serhat KocamanogluHaydar Sahinoglu
Jun 13, 2002·Acta Anaesthesiologica Scandinavica·Rogerio L R VideiraM Brandao Neto
Sep 16, 2003·Clinical Obstetrics and Gynecology·David Wlody
Aug 29, 2000·Anesthesia and Analgesia·J Whiteside
Mar 25, 2016·The Indian Journal of Surgery·Pawan AgarwalD Sharma
Oct 4, 2006·Current Opinion in Anaesthesiology·H Breivik
May 7, 2008·Current Opinion in Anaesthesiology·J Sudharma RanasingheDavid J Birnbach
Jan 23, 1999·Anesthesiology·J S Welch
May 31, 2011·Anesthesiology Clinics·Terese T Horlocker
Nov 16, 2010·International Journal of Obstetric Anesthesia·C L BradburyI Suri
Oct 4, 2008·Best Practice & Research. Clinical Anaesthesiology·Terese T Horlocker, Denise J Wedel
Mar 6, 2008·Anesthesiology Clinics·Felicity Reynolds
Oct 26, 2005·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Yoichi ShimadaHiroshi Oya
Feb 13, 2001·The Journal of Hospital Infection·S Dawson
Oct 14, 2003·Regional Anesthesia and Pain Medicine·E Alp YenturSuheyla Surucuoglu
Feb 19, 2008·Clinics in Perinatology·David J Birnbach, J Sudharma Ranasinghe
Jun 30, 2000·Annales Françaises D'anesthèsie Et De Rèanimation·P GorceJ L Pourriat
Jan 25, 2006·British Journal of Anaesthesia·S GrewalJ A W Wildsmith

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